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10.1007/s00392-020-01683-0

http://scihub22266oqcxt.onion/10.1007/s00392-020-01683-0
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32537662!7293880!32537662
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suck abstract from ncbi


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pmid32537662      Clin+Res+Cardiol 2020 ; 109 (12): 1491-1499
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  • Impaired cardiac function is associated with mortality in patients with acute COVID-19 infection #MMPMID32537662
  • Rath D; Petersen-Uribe A; Avdiu A; Witzel K; Jaeger P; Zdanyte M; Heinzmann D; Tavlaki E; Muller K; Gawaz MP
  • Clin Res Cardiol 2020[Dec]; 109 (12): 1491-1499 PMID32537662show ga
  • BACKGROUND: COVID-19 infection may cause severe respiratory distress and is associated with increased morbidity and mortality. Impaired cardiac function and/or pre-existing cardiovascular disease may be associated with poor prognosis. In the present study, we report a comprehensive cardiovascular characterization in the first consecutive collective of patients that was admitted and treated at the University Hospital of Tubingen, Germany. METHODS: 123 consecutive patients with COVID-19 were included. Routine blood sampling, transthoracic echocardiography and electrocardiography were performed at hospital admission. RESULTS: We found that impaired left-ventricular and right-ventricular function as well as tricuspid regurgitation > grade 1 were significantly associated with higher mortality. Furthermore, elevated levels of myocardial distress markers (troponin-I and NT pro-BNP) were associated with poor prognosis in this patient collective. CONCLUSION: Impaired cardiac function is associated with poor prognosis in COVID-19 positive patients. Consequently, treatment of these patients should include careful guideline-conform cardiovascular evaluation and treatment. Thus, formation of a competent Cardio-COVID-19 team may represent a major clinical measure to optimize therapy of cardiovascular patients during this pandemic.
  • |*Ventricular Function, Left[MESH]
  • |*Ventricular Function, Right[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/diagnosis/*mortality/physiopathology/therapy[MESH]
  • |Female[MESH]
  • |Germany[MESH]
  • |Hospital Mortality[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Prognosis[MESH]
  • |Prospective Studies[MESH]
  • |Risk Assessment[MESH]
  • |Risk Factors[MESH]
  • |Time Factors[MESH]
  • |Tricuspid Valve Insufficiency/diagnosis/*mortality/physiopathology/therapy[MESH]
  • |Ventricular Dysfunction, Left/diagnosis/*mortality/physiopathology/therapy[MESH]


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