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10.1136/bjophthalmol-2020-316776 http://scihub22266oqcxt.onion/10.1136/bjophthalmol-2020-316776 32586933!7313529!32586933     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32586933.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Br+J+Ophthalmol 2021 ; 105 (5): 639-647 Nephropedia Template TP {{tp|p=32586933|t=2021. Evolving consensus for immunomodulatory therapy in non-infectious uveitis during the COVID-19 pandemic |pdf=|usr=}}{{32586933}} gab.com Text Evolving consensus for immunomodulatory therapy in non-infectious uveitis during the COVID-19 pandemic JO: Br J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=32586933 #FOAvip BACKGROUND: Immunomodulatory therapy (IMT) is often considered for systemic treatment of non-infectious uveitis (NIU). During the evolving coronavirus disease-2019 (COVID-19) pandemic, given the concerns related to IMT and the increased risk of infections, an urgent need for guidance on the management of IMT in patients with uveitis has emerged. METHODS: A cross-sectional survey of international uveitis experts was conducted. An expert steering committee identified clinical questions on the use of IMT in patients with NIU during the COVID-19 pandemic. Using an interactive online questionnaire, guided by background experience and knowledge, 139 global uveitis experts generated consensus statements for IMT. In total, 216 statements were developed around when to initiate, continue, decrease and stop systemic and local corticosteroids, conventional immunosuppressive agents and biologics in patients with NIU. Thirty-one additional questions were added, related to general recommendations, including the use of non-steroidal anti-inflammatory drugs (NSAIDs) and hydroxychloroquine. RESULTS: Highest consensus was achieved for not initiating IMT in patients who have suspected or confirmed COVID-19, and for using local over systemic corticosteroid therapy in patients who are at high-risk and very high-risk for severe or fatal COVID-19. While there was a consensus in starting or initiating NSAIDs for the treatment of scleritis in healthy patients, there was no consensus in starting hydroxychloroquine in any risk groups. CONCLUSION: Consensus guidelines were proposed based on global expert opinion and practical experience to bridge the gap between clinical needs and the absence of medical evidence, to guide the treatment of patients with NIU during the COVID-19 pandemic. Twit Text FOAVip Evolving consensus for immunomodulatory therapy in non-infectious uveitis during the COVID-19 pandemic ????Br J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=32586933 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32586933 #FOAvip English Wikipedia <ref>{{Cite pmid|32586933}}</ref> Evolving consensus for immunomodulatory therapy in non-infectious uveitis during the COVID-19 pandemic #MMPMID32586933 Agrawal R; Testi I; Lee CS; Tsui E; Blazes M; Thorne JE; Okada AA; Smith JR; McCluskey PJ; Kempen JH; Tappeiner C; Agarwal M; Bodaghi B; Nguyen QD; Gupta V; De Smet MD; Zierhut M; Pavesio C Br J Ophthalmol 2021[May]; 105 (5): 639-647 PMID32586933show ga BACKGROUND: Immunomodulatory therapy (IMT) is often considered for systemic treatment of non-infectious uveitis (NIU). During the evolving coronavirus disease-2019 (COVID-19) pandemic, given the concerns related to IMT and the increased risk of infections, an urgent need for guidance on the management of IMT in patients with uveitis has emerged. METHODS: A cross-sectional survey of international uveitis experts was conducted. An expert steering committee identified clinical questions on the use of IMT in patients with NIU during the COVID-19 pandemic. Using an interactive online questionnaire, guided by background experience and knowledge, 139 global uveitis experts generated consensus statements for IMT. In total, 216 statements were developed around when to initiate, continue, decrease and stop systemic and local corticosteroids, conventional immunosuppressive agents and biologics in patients with NIU. Thirty-one additional questions were added, related to general recommendations, including the use of non-steroidal anti-inflammatory drugs (NSAIDs) and hydroxychloroquine. RESULTS: Highest consensus was achieved for not initiating IMT in patients who have suspected or confirmed COVID-19, and for using local over systemic corticosteroid therapy in patients who are at high-risk and very high-risk for severe or fatal COVID-19. While there was a consensus in starting or initiating NSAIDs for the treatment of scleritis in healthy patients, there was no consensus in starting hydroxychloroquine in any risk groups. CONCLUSION: Consensus guidelines were proposed based on global expert opinion and practical experience to bridge the gap between clinical needs and the absence of medical evidence, to guide the treatment of patients with NIU during the COVID-19 pandemic. |*Immunomodulation[MESH] |*SARS-CoV-2[MESH] |COVID-19/*epidemiology[MESH] |Clinical Decision-Making[MESH] |Consensus[MESH] |Cross-Sectional Studies[MESH] |Glucocorticoids/*therapeutic use[MESH] |Humans[MESH] |Immunosuppressive Agents/*therapeutic use[MESH] |Practice Guidelines as Topic[MESH] |Risk Assessment[MESH] |Surveys and Questionnaires[MESH]Evolving consensus for immunomodulatory therapy in non-infectious uvei(epmc).pdf DeepDyve Pubget Overpricing