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10.1016/j.transci.2020.102855 http://scihub22266oqcxt.onion/10.1016/j.transci.2020.102855 32636114!7316033!32636114     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32636114&cmd=llinks): Failed to open stream: HTTP request failed! 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Extracorporeal blood purification treatment options for COVID-19: The role of immunoadsorption |pdf=|usr=}}{{32636114}} gab.com Text Extracorporeal blood purification treatment options for COVID-19: The role of immunoadsorption JO: Transfus Apher Sci http://www.kidney.de/pget.php?&tw=1&pmid=32636114 #FOAvip The activation of the innate and adaptive immune systems by SARS-CoV-2 causes the release of several inflammatory cytokines, including IL-6. The inflammatory hypercytokinemia causes immunopathological changes in the lungs including vascular leakage, and alveolar edema. As a result of these changes in the lungs, hypoxia and acute respiratory distress syndrome occur in patients with COVID-19. Even though there are clinical trials on the development of therapeutics and vaccines, there are currently no licensed vaccines or therapeutics for COVID-19. Pharmacological approaches have shown poor results in sepsis-like syndromes caused by the hypercytokinemia. Suppressing the cytokine storm is an important way to prevent the organ damage in patients with COVID-19. Extracorporeal blood purification could be proposed as an adjunctive therapy for sepsis, aiming to control the associated dysregulation of the immune system, which is known to protect organ functions. Several extracorporeal blood purification therapies are now available, and most of them target endotoxins and/or the cytokines and aim improving the immune response. For this purpose, plasmapheresis and immunoadsorption may be an important adjunctive treatment option to manage the complications caused by cytokine storm in critically ill patients with COVID-19. Twit Text FOAVip Extracorporeal blood purification treatment options for COVID-19: The role of immunoadsorption ????Transfus Apher Sci http://www.kidney.de/pget.php?&tw=1&pmid=32636114 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32636114 #FOAvip English Wikipedia <ref>{{Cite pmid|32636114}}</ref> Extracorporeal blood purification treatment options for COVID-19: The role of immunoadsorption #MMPMID32636114 Yigenoglu TN; Ulas T; Dal MS; Korkmaz S; Erkurt MA; Altuntas F Transfus Apher Sci 2020[Aug]; 59 (4): 102855 PMID32636114show ga The activation of the innate and adaptive immune systems by SARS-CoV-2 causes the release of several inflammatory cytokines, including IL-6. The inflammatory hypercytokinemia causes immunopathological changes in the lungs including vascular leakage, and alveolar edema. As a result of these changes in the lungs, hypoxia and acute respiratory distress syndrome occur in patients with COVID-19. Even though there are clinical trials on the development of therapeutics and vaccines, there are currently no licensed vaccines or therapeutics for COVID-19. Pharmacological approaches have shown poor results in sepsis-like syndromes caused by the hypercytokinemia. Suppressing the cytokine storm is an important way to prevent the organ damage in patients with COVID-19. Extracorporeal blood purification could be proposed as an adjunctive therapy for sepsis, aiming to control the associated dysregulation of the immune system, which is known to protect organ functions. Several extracorporeal blood purification therapies are now available, and most of them target endotoxins and/or the cytokines and aim improving the immune response. For this purpose, plasmapheresis and immunoadsorption may be an important adjunctive treatment option to manage the complications caused by cytokine storm in critically ill patients with COVID-19. |*Betacoronavirus[MESH] |*Extracorporeal Circulation[MESH] |*Pandemics[MESH] |*Plasmapheresis/methods[MESH] |COVID-19[MESH] |COVID-19 Drug Treatment[MESH] |Coronavirus Infections/blood/complications/drug therapy/*therapy[MESH] |Cytokine Release Syndrome/blood/etiology/prevention & control[MESH] |Cytokines/blood[MESH] |Humans[MESH] |Plasma Exchange[MESH] |Pneumonia, Viral/blood/complications/*therapy[MESH] |Respiratory Distress Syndrome/etiology[MESH]Extracorporeal blood purification treatment options for COVID-19: The (epmc).pdf DeepDyve Pubget Overpricing