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10.1186/s12879-020-05245-7 http://scihub22266oqcxt.onion/10.1186/s12879-020-05245-7 32677909!7364136!32677909     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32677909&cmd=llinks): Failed to open stream: HTTP request failed! 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A COVID-19 patient with multiple negative results for PCR assays outside Wuhan, China: a case report |pdf=|usr=}}{{32677909}} gab.com Text A COVID-19 patient with multiple negative results for PCR assays outside Wuhan, China: a case report JO: BMC Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32677909 #FOAvip BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a public health emergency of major international concern. Real-time RT-PCR assays are recommended for diagnosis of COVID-19. Here we report a rare case of COVID-19 with multiple negative results for PCR assays outside Wuhan, China. CASE PRESENTATION: A 32-year old male was admitted to our hospital because of 6 days of unexplained fever on January 29, 2020. He had come from Wuhan city 10 days before admission. Five days before admission, no abnormality was noted in laboratory test, chest radiography, and nasopharyngeal swab test for the SARS-CoV-2 nucleic acid. The patient was treated with ibuprofen for alleviating fever. On admission, chest computed tomography showed multiple ground-glass opacities in right lower lung field. COVID-19 was suspected. Three times of nasopharyngeal swab specimens were collected after admission. However, none of the specimens were positive. The patient was confirmed with COVID-19 after fifth SARS-CoV-2 nucleic acid test. He was treated with lopinavir/ritonavir, recombinant human interferon alfa-2b inhalation, methylprednisolone. After 18 days of treatment, he was discharged with improved symptoms, lung lesions and negative results of nasopharyngeal swab. CONCLUSION: This case reminds clinician that a patient with high clinical suspicion of COVID-19 but multiple negative RT-PCR result should not be taken out of isolation. A combination of patient's exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. Repeat swab tests are helpful in diagnosis for this kind of patients. Twit Text FOAVip A COVID-19 patient with multiple negative results for PCR assays outside Wuhan, China: a case report ????BMC Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=32677909 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32677909 #FOAvip English Wikipedia <ref>{{Cite pmid|32677909}}</ref> A COVID-19 patient with multiple negative results for PCR assays outside Wuhan, China: a case report #MMPMID32677909 Chen LD; Li H; Ye YM; Wu Z; Huang YP; Zhang WL; Lin L BMC Infect Dis 2020[Jul]; 20 (1): 517 PMID32677909show ga BACKGROUND: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a public health emergency of major international concern. Real-time RT-PCR assays are recommended for diagnosis of COVID-19. Here we report a rare case of COVID-19 with multiple negative results for PCR assays outside Wuhan, China. CASE PRESENTATION: A 32-year old male was admitted to our hospital because of 6 days of unexplained fever on January 29, 2020. He had come from Wuhan city 10 days before admission. Five days before admission, no abnormality was noted in laboratory test, chest radiography, and nasopharyngeal swab test for the SARS-CoV-2 nucleic acid. The patient was treated with ibuprofen for alleviating fever. On admission, chest computed tomography showed multiple ground-glass opacities in right lower lung field. COVID-19 was suspected. Three times of nasopharyngeal swab specimens were collected after admission. However, none of the specimens were positive. The patient was confirmed with COVID-19 after fifth SARS-CoV-2 nucleic acid test. He was treated with lopinavir/ritonavir, recombinant human interferon alfa-2b inhalation, methylprednisolone. After 18 days of treatment, he was discharged with improved symptoms, lung lesions and negative results of nasopharyngeal swab. CONCLUSION: This case reminds clinician that a patient with high clinical suspicion of COVID-19 but multiple negative RT-PCR result should not be taken out of isolation. A combination of patient's exposure history, clinical manifestations, laboratory tests, and typical imaging findings plays a vital role in making preliminary diagnosis and guide early isolation and treatment. Repeat swab tests are helpful in diagnosis for this kind of patients. |*Negative Results[MESH] |Adult[MESH] |Betacoronavirus/genetics/*isolation & purification[MESH] |COVID-19[MESH] |China/epidemiology[MESH] |Coronavirus Infections/*diagnosis/diagnostic imaging/physiopathology/*virology[MESH] |Fever/etiology/virology[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |Pandemics[MESH] |Pneumonia, Viral/*diagnosis/diagnostic imaging/physiopathology/*virology[MESH] |Quarantine[MESH] |Radiography[MESH] |Real-Time Polymerase Chain Reaction[MESH] |SARS-CoV-2[MESH] |Sensitivity and Specificity[MESH] |Tomography, X-Ray Computed[MESH]A COVID-19 patient with multiple negative results for PCR assays outsi(epmc).pdf DeepDyve Pubget Overpricing