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10.5811/westjem.2020.6.47919 http://scihub22266oqcxt.onion/10.5811/westjem.2020.6.47919 32726241!7390589!32726241     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=32726241&cmd=llinks): Failed to open stream: HTTP request failed! 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Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City |pdf=|usr=}}{{32726241}} gab.com Text Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City JO: West J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32726241 #FOAvip INTRODUCTION: Rapid spread of coronavirus disease 2019 (COVID-19) in the United States, especially in New York City (NYC), led to a tremendous increase in hospitalizations and mortality. There is very limited data available that associates outcomes during hospitalization in patients with COVID-19. METHODS: In this retrospective cohort study, we reviewed the health records of patients with COVID-19 who were admitted from March 9-April 9, 2020, to a community hospital in NYC. Subjects with confirmed reverse transcriptase-polymerase chain reaction (RT-PCR) of the nasopharyngeal swab for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) were included. We collected data related to demographics, laboratory results, and outcome of hospitalization. Outcome was measured based on whether the patient was discharged home or died during hospitalization. RESULTS: There were 888 consecutive admissions with COVID-19 during the study period, of which 513 were excluded with pending outcome or incomplete information. We included a total of 375 patients in the study, of whom 215 (57%) survived and 160 (43%) died during hospitalization. The majority of patients were male (63%) and of Hispanic origin (66%) followed by Blacks (25%), and others (9%). Hypertension (60%) stands out to be the most common comorbidity followed by diabetes mellitus (47%), cardiovascular disease (17%), chronic kidney disease (17%), and human immunodeficiency virus/acquired immunodeficiency syndrome (9%). On multiple regression analysis, increasing odds of mortality during hospitalization was associated with older age (odds ratio [OR] 1.04; 95% confidence interval [CI], 1.01-1.06 per year increase; p < 0.0001), admission D-dimer more than 1000 nanograms per milliliter (ng/mL) (OR 3.16; 95% CI, 1.75-5.73; p<0.0001), admission C-reactive protein (CRP) levels of more than 200 milligrams per liter (mg/L) (OR 2.43; 95% CI, 1.36-4.34; p = 0.0028), and admission lymphopenia (OR 2.63; CI, 1.47-4.69; p 0.0010). CONCLUSION: In this retrospective cohort study originating in NYC, older age, admission levels of D-dimer of more than 1000 ng/mL, CRP of more than 200 mg/L and lymphopenia were associated with mortality in individuals hospitalized for COVID-19. We recommend using these risk factors on admission to triage patients to critical care units or surge units to maximize the use of surge capacity beds. Twit Text FOAVip Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City ????West J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=32726241 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32726241 #FOAvip English Wikipedia <ref>{{Cite pmid|32726241}}</ref> Predictors of Mortality in Adults Admitted with COVID-19: Retrospective Cohort Study from New York City #MMPMID32726241 Chilimuri S; Sun H; Alemam A; Mantri N; Shehi E; Tejada J; Yugay A; Nayudu SK West J Emerg Med 2020[Jul]; 21 (4): 779-784 PMID32726241show ga INTRODUCTION: Rapid spread of coronavirus disease 2019 (COVID-19) in the United States, especially in New York City (NYC), led to a tremendous increase in hospitalizations and mortality. There is very limited data available that associates outcomes during hospitalization in patients with COVID-19. METHODS: In this retrospective cohort study, we reviewed the health records of patients with COVID-19 who were admitted from March 9-April 9, 2020, to a community hospital in NYC. Subjects with confirmed reverse transcriptase-polymerase chain reaction (RT-PCR) of the nasopharyngeal swab for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) were included. We collected data related to demographics, laboratory results, and outcome of hospitalization. Outcome was measured based on whether the patient was discharged home or died during hospitalization. RESULTS: There were 888 consecutive admissions with COVID-19 during the study period, of which 513 were excluded with pending outcome or incomplete information. We included a total of 375 patients in the study, of whom 215 (57%) survived and 160 (43%) died during hospitalization. The majority of patients were male (63%) and of Hispanic origin (66%) followed by Blacks (25%), and others (9%). Hypertension (60%) stands out to be the most common comorbidity followed by diabetes mellitus (47%), cardiovascular disease (17%), chronic kidney disease (17%), and human immunodeficiency virus/acquired immunodeficiency syndrome (9%). On multiple regression analysis, increasing odds of mortality during hospitalization was associated with older age (odds ratio [OR] 1.04; 95% confidence interval [CI], 1.01-1.06 per year increase; p < 0.0001), admission D-dimer more than 1000 nanograms per milliliter (ng/mL) (OR 3.16; 95% CI, 1.75-5.73; p<0.0001), admission C-reactive protein (CRP) levels of more than 200 milligrams per liter (mg/L) (OR 2.43; 95% CI, 1.36-4.34; p = 0.0028), and admission lymphopenia (OR 2.63; CI, 1.47-4.69; p 0.0010). CONCLUSION: In this retrospective cohort study originating in NYC, older age, admission levels of D-dimer of more than 1000 ng/mL, CRP of more than 200 mg/L and lymphopenia were associated with mortality in individuals hospitalized for COVID-19. We recommend using these risk factors on admission to triage patients to critical care units or surge units to maximize the use of surge capacity beds. |*Betacoronavirus[MESH] |*Hospitalization[MESH] |Adult[MESH] |Age Factors[MESH] |Aged[MESH] |Aged, 80 and over[MESH] |C-Reactive Protein/analysis[MESH] |COVID-19[MESH] |Cardiovascular Diseases/epidemiology[MESH] |Cohort Studies[MESH] |Comorbidity[MESH] |Coronavirus Infections/*mortality[MESH] |Diabetes Mellitus/epidemiology[MESH] |Female[MESH] |Fibrin Fibrinogen Degradation Products/analysis[MESH] |HIV Infections/epidemiology[MESH] |Hospitals, Community[MESH] |Humans[MESH] |Hypertension/epidemiology[MESH] |Lymphopenia/epidemiology[MESH] |Male[MESH] |Middle Aged[MESH] |New York City/epidemiology[MESH] |Pandemics[MESH] |Pneumonia, Viral/*mortality[MESH] |Racial Groups/statistics & numerical data[MESH] |Renal Insufficiency, Chronic/epidemiology[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |SARS-CoV-2[MESH]Predictors of Mortality in Adults Admitted with COVID-19: Retrospectiv(epmc).pdf DeepDyve Pubget Overpricing