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Clinical and histopathological findings of cutaneous manifestations of COVID-19 patients #MMPMID32779817
Brandao MGSA; Barros LM; de Aquino Mendonca J; de Oliveira AR; de Araujo TM; Veras VS
Dermatol Ther 2020[Nov]; 33 (6): e13926 PMID32779817show ga
Coronavirus disease (COVID-19) became pandemic since this is a disease with a high infection rate. The study's object is to identify clinical and histopathological findings of cutaneous manifestations of COVID-19 patients. The evidence was analyzed in PubMed, CINAHL, Cochrane, Web of Science, and Scopus, with the search strategy (covid 19 OR covid-19 OR corona OR coronavirus OR sars-cov-2) AND (cutaneous or cutaneous manifestations OR), and 17 studies were included, involving 351 cases with COVID19 and skin manifestations. The lesions were classified mainly as maculopapular, erythematous, vesicular, and urticarial. Histopathological analyses suggest a predominance of spongiosis, perivascular infiltrate of lymphocytes, and thrombogenic vasculopathy.