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10.1002/smll.202003010 http://scihub22266oqcxt.onion/10.1002/smll.202003010 32815251!ä!32815251 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32815251.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Small 2020 ; 16 (38): e2003010 Nephropedia Template TP {{tp|p=32815251|t=2020. ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation |pdf=|usr=}}{{32815251}} gab.com Text ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation JO: Small http://www.kidney.de/pget.php?&tw=1&pmid=32815251 #FOAvip Currently, mesenchymal stem cells (MSCs)-based therapies for bone regeneration and treatments have gained significant attention in clinical research. Though many chemical and physical cues which influence the osteogenic differentiation of MSCs have been explored, scaffolds combining the benefits of Zn(2+) ions and unique nanostructures may become an ideal interface to enhance osteogenic and anti-infective capabilities simultaneously. In this work, motivated by the enormous advantages of Zn-based metal-organic framework-derived nanocarbons, C-ZnO nanocarbons-modified fibrous scaffolds for stem cell-based osteogenic differentiation are constructed. The modified scaffolds show enhanced expression of alkaline phosphatase, bone sialoprotein, vinculin, and a larger cell spreading area. Meanwhile, the caging of ZnO nanoparticles can allow the slow release of Zn(2+) ions, which not only activate various signaling pathways to guide osteogenic differentiation but also prevent the potential bacterial infection of implantable scaffolds. Overall, this study may provide new insight for designing stem cell-based nanostructured fibrous scaffolds with simultaneously enhanced osteogenic and anti-infective capabilities. Twit Text FOAVip ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation ????Small http://www.kidney.de/pget.php?&tw=1&pmid=32815251 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32815251 #FOAvip English Wikipedia <ref>{{Cite pmid|32815251}}</ref> ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteogenic Differentiation #MMPMID32815251 Xia Y; Fan X; Yang H; Li L; He C; Cheng C; Haag R Small 2020[Sep]; 16 (38): e2003010 PMID32815251show ga Currently, mesenchymal stem cells (MSCs)-based therapies for bone regeneration and treatments have gained significant attention in clinical research. Though many chemical and physical cues which influence the osteogenic differentiation of MSCs have been explored, scaffolds combining the benefits of Zn(2+) ions and unique nanostructures may become an ideal interface to enhance osteogenic and anti-infective capabilities simultaneously. In this work, motivated by the enormous advantages of Zn-based metal-organic framework-derived nanocarbons, C-ZnO nanocarbons-modified fibrous scaffolds for stem cell-based osteogenic differentiation are constructed. The modified scaffolds show enhanced expression of alkaline phosphatase, bone sialoprotein, vinculin, and a larger cell spreading area. Meanwhile, the caging of ZnO nanoparticles can allow the slow release of Zn(2+) ions, which not only activate various signaling pathways to guide osteogenic differentiation but also prevent the potential bacterial infection of implantable scaffolds. Overall, this study may provide new insight for designing stem cell-based nanostructured fibrous scaffolds with simultaneously enhanced osteogenic and anti-infective capabilities. |Alkaline Phosphatase/metabolism[MESH] |Carbon/*chemistry[MESH] |Cell Differentiation/physiology[MESH] |Cells, Cultured[MESH] |Humans[MESH] |Integrin-Binding Sialoprotein/metabolism[MESH] |Materials Testing[MESH] |Mesenchymal Stem Cells/*cytology/metabolism[MESH] |Microscopy, Electron, Scanning[MESH] |Nanofibers/*chemistry/ultrastructure[MESH] |Osteogenesis/*physiology[MESH] |Signal Transduction[MESH] |Tissue Engineering[MESH] |Tissue Scaffolds/*chemistry[MESH] |Vinculin/metabolism[MESH]ZnO/Nanocarbons-Modified Fibrous Scaffolds for Stem Cell-Based Osteoge(epmc).pdf DeepDyve Pubget Overpricing