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Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing #MMPMID32848231
Allen WE; Altae-Tran H; Briggs J; Jin X; McGee G; Shi A; Raghavan R; Kamariza M; Nova N; Pereta A; Danford C; Kamel A; Gothe P; Milam E; Aurambault J; Primke T; Li W; Inkenbrandt J; Huynh T; Chen E; Lee C; Croatto M; Bentley H; Lu W; Murray R; Travassos M; Coull BA; Openshaw J; Greene CS; Shalem O; King G; Probasco R; Cheng DR; Silbermann B; Zhang F; Lin X
Nat Hum Behav 2020[Sep]; 4 (9): 972-982 PMID32848231show ga
Despite the widespread implementation of public health measures, coronavirus disease 2019 (COVID-19) continues to spread in the United States. To facilitate an agile response to the pandemic, we developed How We Feel, a web and mobile application that collects longitudinal self-reported survey responses on health, behaviour and demographics. Here, we report results from over 500,000 users in the United States from 2 April 2020 to 12 May 2020. We show that self-reported surveys can be used to build predictive models to identify likely COVID-19-positive individuals. We find evidence among our users for asymptomatic or presymptomatic presentation; show a variety of exposure, occupational and demographic risk factors for COVID-19 beyond symptoms; reveal factors for which users have been SARS-CoV-2 PCR tested; and highlight the temporal dynamics of symptoms and self-isolation behaviour. These results highlight the utility of collecting a diverse set of symptomatic, demographic, exposure and behavioural self-reported data to fight the COVID-19 pandemic.