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10.1016/j.ijheh.2020.113621

http://scihub22266oqcxt.onion/10.1016/j.ijheh.2020.113621
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suck abstract from ncbi


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pmid32911123      Int+J+Hyg+Environ+Health 2020 ; 230 (ä): 113621
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  • Metropolitan wastewater analysis for COVID-19 epidemiological surveillance #MMPMID32911123
  • Randazzo W; Cuevas-Ferrando E; Sanjuan R; Domingo-Calap P; Sanchez G
  • Int J Hyg Environ Health 2020[Sep]; 230 (ä): 113621 PMID32911123show ga
  • The COVID-19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a rapidly emerging pandemic which has enforced extreme containment measures worldwide. In the absence of a vaccine or efficient treatment, cost-effective epidemiological surveillance strategies are urgently needed. Here, we have used RT-qPCR for SARS-CoV-2 detection in a series of longitudinal metropolitan wastewaters samples collected from February to April 2020, during the earliest stages of the epidemic in the Region of Valencia, Spain. We were able to consistently detect SARS-CoV-2 RNA in samples taken in late February, when communicated cases in that region were only incipient. We also find that the wastewater viral RNA context increased rapidly and anticipated the subsequent ascent in the number of declared cases. Our results strongly suggest that the virus was undergoing community transmission earlier than previously believed, and suggest that wastewater analysis could be sensitive and cost-effective strategy for COVID-19 epidemiological surveillance. Routine implementation of this surveillance tool would significantly improve our preparedness against new or re-occurring viral outbreaks.
  • |*COVID-19[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |RNA, Viral[MESH]
  • |SARS-CoV-2[MESH]


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