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10.4149/av_2020_302 http://scihub22266oqcxt.onion/10.4149/av_2020_302 32985202!ä!32985202 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\32985202.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Acta+Virol 2020 ; 64 (3): 281-287 Nephropedia Template TP {{tp|p=32985202|t=2020. SARS-CoV-2: Zoonotic origin of pandemic coronavirus |pdf=|usr=}}{{32985202}} gab.com Text SARS-CoV-2: Zoonotic origin of pandemic coronavirus JO: Acta Virol http://www.kidney.de/pget.php?&tw=1&pmid=32985202 #FOAvip A novel disease, of unknown origin, causing a deadly pneumonia of human patients was reported in December 2019 in Wuhan, Hubei province of China. Later called coronavirus disease (COVID-19), it rapidly spread across China and worldwide. Intensive research revealed that the etiological agent of the global COVID-19 pandemic was a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 genome contains typical coronavirus genes but the receptor binding domain (RBD) in the S protein is highly specific. The site for furin-like protease cleavage of the S protein into S1 and S2 subunits is also unique. Further analyses suggested that SARS-CoV-2 is of zoonotic origin. The analysis of the SARS-CoV-2 genome, especially the S gene, shows that natural evolutionary process between a bat-CoV and a pangolin-CoV or other animal coronavirus could have been important in creating SARS-CoV-2, with transmission of novel virus to the human population. On the other hand, new analyses indicate that SARS-CoV-2 is not a recombinant virus. Keywords: COVID-19; SARS-CoV-2; genome; bat coronavirus; pangolin coronavirus. Twit Text FOAVip SARS-CoV-2: Zoonotic origin of pandemic coronavirus ????Acta Virol http://www.kidney.de/pget.php?&tw=1&pmid=32985202 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=32985202 #FOAvip English Wikipedia <ref>{{Cite pmid|32985202}}</ref> SARS-CoV-2: Zoonotic origin of pandemic coronavirus #MMPMID32985202 Vilcek S Acta Virol 2020[]; 64 (3): 281-287 PMID32985202show ga A novel disease, of unknown origin, causing a deadly pneumonia of human patients was reported in December 2019 in Wuhan, Hubei province of China. Later called coronavirus disease (COVID-19), it rapidly spread across China and worldwide. Intensive research revealed that the etiological agent of the global COVID-19 pandemic was a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 genome contains typical coronavirus genes but the receptor binding domain (RBD) in the S protein is highly specific. The site for furin-like protease cleavage of the S protein into S1 and S2 subunits is also unique. Further analyses suggested that SARS-CoV-2 is of zoonotic origin. The analysis of the SARS-CoV-2 genome, especially the S gene, shows that natural evolutionary process between a bat-CoV and a pangolin-CoV or other animal coronavirus could have been important in creating SARS-CoV-2, with transmission of novel virus to the human population. On the other hand, new analyses indicate that SARS-CoV-2 is not a recombinant virus. Keywords: COVID-19; SARS-CoV-2; genome; bat coronavirus; pangolin coronavirus. |Animals[MESH] |Betacoronavirus/*genetics[MESH] |COVID-19[MESH] |Chiroptera/virology[MESH] |Coronavirus Infections/*etiology[MESH] |Eutheria[MESH] |Humans[MESH] |Pandemics[MESH] |Pneumonia, Viral/*etiology[MESH] |SARS-CoV-2[MESH] |Spike Glycoprotein, Coronavirus/genetics[MESH]SARS-CoV-2: Zoonotic origin of pandemic coronavirus (epmc).pdf DeepDyve Pubget Overpricing