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10.1111/ene.14580 http://scihub22266oqcxt.onion/10.1111/ene.14580 33043560!7675416!33043560     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33043560&cmd=llinks): Failed to open stream: HTTP request failed! 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COVID-19 pandemic and mental distress in multiple sclerosis: Implications for clinical management |pdf=|usr=}}{{33043560}} gab.com Text COVID-19 pandemic and mental distress in multiple sclerosis: Implications for clinical management JO: Eur J Neurol http://www.kidney.de/pget.php?&tw=1&pmid=33043560 #FOAvip BACKGROUND AND PURPOSE: In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiatric symptoms in an Italian MS population during the COVID-19 lockdown, in order to identify potentially modifiable factors that could inform clinical management of mental distress in people with MS. METHODS: We explored the relationship between mental distress, disability and coping strategies in the Italian MS population under lockdown. Structural equation modeling was applied to information collected via web survey to identify modifiable factors that could account for mental distress. RESULTS: A total of 845 participants (497 with MS and 348 controls) were included in the study. The MS group had higher scores than the control group for depression (p = 0.005), but not for anxiety, emotional dyscontrol or sleep disturbances. The structural equation modeling explained 74% of the variance observed in depression score. Within the model, three latent factors were characterized from measured variables: motor disability and cognitive dysfunction contributed to disability (beta = 0.509 and beta = 0.836; p < 0.001); positive attitude and exercise contributed to active attitude (beta = 0.386 and beta = 0.297; p < 0.001); and avoidance, social support and watching television contributed to passive attitude (beta = 0.301, beta = 0.243 and beta = 0.212; p < 0.001). With regard to the relationship between latent factors and their influence on depression, disability contributed to passive attitude (beta = 0.855; p < 0.001), while both passive and active attitude significantly influenced depression (beta = 0.729 and beta = -0.456; p < 0.001). CONCLUSION: As a practical implication of our model, favoring exercise would enhance active attitude and its positive impact on mental well-being while, at the same time, reducing the negative impact of disability on depression, representing a valuable tool in facing COVID-19-related mental distress. Twit Text FOAVip COVID-19 pandemic and mental distress in multiple sclerosis: Implications for clinical management ????Eur J Neurol http://www.kidney.de/pget.php?&tw=1&pmid=33043560 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33043560 #FOAvip English Wikipedia <ref>{{Cite pmid|33043560}}</ref> COVID-19 pandemic and mental distress in multiple sclerosis: Implications for clinical management #MMPMID33043560 Costabile T; Carotenuto A; Lavorgna L; Borriello G; Moiola L; Inglese M; Petruzzo M; Trojsi F; Ianniello A; Nozzolillo A; Cellerino M; Boffa G; Rosa L; Servillo G; Moccia M; Bonavita S; Filippi M; Lanzillo R; Brescia Morra V; Petracca M Eur J Neurol 2021[Oct]; 28 (10): 3375-3383 PMID33043560show ga BACKGROUND AND PURPOSE: In multiple sclerosis (MS), disease-related factors and dysfunctional coping might favor the development of mental distress induced by COVID-19 containment measures. Aim of this study was exploring the relationship between disability, coping strategies, daily life reorganization and neuropsychiatric symptoms in an Italian MS population during the COVID-19 lockdown, in order to identify potentially modifiable factors that could inform clinical management of mental distress in people with MS. METHODS: We explored the relationship between mental distress, disability and coping strategies in the Italian MS population under lockdown. Structural equation modeling was applied to information collected via web survey to identify modifiable factors that could account for mental distress. RESULTS: A total of 845 participants (497 with MS and 348 controls) were included in the study. The MS group had higher scores than the control group for depression (p = 0.005), but not for anxiety, emotional dyscontrol or sleep disturbances. The structural equation modeling explained 74% of the variance observed in depression score. Within the model, three latent factors were characterized from measured variables: motor disability and cognitive dysfunction contributed to disability (beta = 0.509 and beta = 0.836; p < 0.001); positive attitude and exercise contributed to active attitude (beta = 0.386 and beta = 0.297; p < 0.001); and avoidance, social support and watching television contributed to passive attitude (beta = 0.301, beta = 0.243 and beta = 0.212; p < 0.001). With regard to the relationship between latent factors and their influence on depression, disability contributed to passive attitude (beta = 0.855; p < 0.001), while both passive and active attitude significantly influenced depression (beta = 0.729 and beta = -0.456; p < 0.001). CONCLUSION: As a practical implication of our model, favoring exercise would enhance active attitude and its positive impact on mental well-being while, at the same time, reducing the negative impact of disability on depression, representing a valuable tool in facing COVID-19-related mental distress. |*COVID-19[MESH] |*Motor Disorders[MESH] |*Multiple Sclerosis/epidemiology[MESH] |*Persons with Disabilities[MESH] |Anxiety[MESH] |Communicable Disease Control[MESH] |Depression/epidemiology[MESH] |Humans[MESH] |Pandemics[MESH] |SARS-CoV-2[MESH]COVID-19 pandemic and mental distress in multiple sclerosis: Implicati(epmc).pdf DeepDyve Pubget Overpricing