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10.1007/s12015-020-10065-y http://scihub22266oqcxt.onion/10.1007/s12015-020-10065-y 33145673!7609374!33145673     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33145673&cmd=llinks): Failed to open stream: HTTP request failed! 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Fate of Hematopoiesis During Aging What Do We Really Know, and What are its Implications?|pdf=|usr=}}{{33145673}} gab.com Text Fate of Hematopoiesis During Aging What Do We Really Know, and What are its Implications JO: Stem Cell Rev Rep http://www.kidney.de/pget.php?&tw=1&pmid=33145673 #FOAvip There is an ongoing shift in demographics such that older persons will outnumber young persons in the coming years, and with it age-associated tissue attrition and increased diseases and disorders. There has been increased information on the association of the aging process with dysregulation of hematopoietic stem (HSC) and progenitor (HPC) cells, and hematopoiesis. This review provides an extensive up-to date summary on the literature of aged hematopoiesis and HSCs placed in context of potential artifacts of the collection and processing procedure, that may not be totally representative of the status of HSCs in their in vivo bone marrow microenvironment, and what the implications of this are for understanding aged hematopoiesis. This review covers a number of interactive areas, many of which have not been adequately explored. There are still many unknowns and mechanistic insights to be elucidated to better understand effects of aging on the hematopoietic system, efforts that will take multidisciplinary approaches, and that could lead to means to ameliorate at least some of the dysregulation of HSCs and HPCs associated with the aging process. Graphical Abstract. Twit Text FOAVip Fate of Hematopoiesis During Aging What Do We Really Know, and What are its Implications ????Stem Cell Rev Rep http://www.kidney.de/pget.php?&tw=1&pmid=33145673 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33145673 #FOAvip English Wikipedia <ref>{{Cite pmid|33145673}}</ref> Fate of Hematopoiesis During Aging What Do We Really Know, and What are its Implications? #MMPMID33145673 Broxmeyer HE; Liu Y; Kapur R; Orschell CM; Aljoufi A; Ropa JP; Trinh T; Burns S; Capitano ML Stem Cell Rev Rep 2020[Dec]; 16 (6): 1020-1048 PMID33145673show ga There is an ongoing shift in demographics such that older persons will outnumber young persons in the coming years, and with it age-associated tissue attrition and increased diseases and disorders. There has been increased information on the association of the aging process with dysregulation of hematopoietic stem (HSC) and progenitor (HPC) cells, and hematopoiesis. This review provides an extensive up-to date summary on the literature of aged hematopoiesis and HSCs placed in context of potential artifacts of the collection and processing procedure, that may not be totally representative of the status of HSCs in their in vivo bone marrow microenvironment, and what the implications of this are for understanding aged hematopoiesis. This review covers a number of interactive areas, many of which have not been adequately explored. There are still many unknowns and mechanistic insights to be elucidated to better understand effects of aging on the hematopoietic system, efforts that will take multidisciplinary approaches, and that could lead to means to ameliorate at least some of the dysregulation of HSCs and HPCs associated with the aging process. Graphical Abstract. |Aging/*physiology[MESH] |Animals[MESH] |Epigenesis, Genetic[MESH] |Hematopoiesis/*physiology[MESH] |Hematopoietic Stem Cells/physiology[MESH] |Humans[MESH] |Microbiota[MESH]Fate of Hematopoiesis During Aging What Do We Really Know, and What a(epmc).pdf DeepDyve Pubget Overpricing