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10.3906/sag-2008-167 http://scihub22266oqcxt.onion/10.3906/sag-2008-167 33155789!7991856!33155789     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33155789&cmd=llinks): Failed to open stream: HTTP request failed! 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Does fludrocortisone treatment cause hypomagnesemia in children with primary adrenal insufficiency?|pdf=|usr=}}{{33155789}} gab.com Text Does fludrocortisone treatment cause hypomagnesemia in children with primary adrenal insufficiency JO: Turk J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=33155789 #FOAvip BACKGROUND/AIM: Aldosterone is a mineralocorticoid that secreted from adrenal glands and a known factor to increase magnesium excretion by direct and indirect effects on renal tubular cells. Although the frequency of hypomagnesemia was found to be approximately 5% in adult studies, there is no study in the literature investigating the frequency of hypomagnesemia in children by using fludrocortisone, which has a mineralocorticoid activity. MATERIALS AND METHODS: A multi-center retrospective study was conducted, including children who were under fludrocortisone treatment for primary adrenal insufficiency and applied to participant pediatric endocrinology outpatient clinics. RESULTS: Forty-three patients (58.1% male, 41.9% prepubertal) included in the study, whose median age was 9.18 (0.61-19) years, and the most common diagnosis among the patients was a salt-wasting form of congenital adrenal hyperplasia (67.4%). Mean serum magnesium level was 2.05 (+/-0.13) mg/dL, and hypomagnesemia was not observed in any of the patients treated with fludrocortisone. None of the patients had increased urinary excretion of magnesium. CONCLUSION: Unlike the studies performed in adults, we could not find any evidence of magnesium wasting effect of fludrocortisone treatment with normal or even high doses in children and adolescents. Twit Text FOAVip Does fludrocortisone treatment cause hypomagnesemia in children with primary adrenal insufficiency ????Turk J Med Sci http://www.kidney.de/pget.php?&tw=1&pmid=33155789 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33155789 #FOAvip English Wikipedia <ref>{{Cite pmid|33155789}}</ref> Does fludrocortisone treatment cause hypomagnesemia in children with primary adrenal insufficiency? #MMPMID33155789 Erbas IM; Altincik SA; Catli G; Unuvar T; Ozhan B; Abaci A; Anik A Turk J Med Sci 2021[Feb]; 51 (1): 231-237 PMID33155789show ga BACKGROUND/AIM: Aldosterone is a mineralocorticoid that secreted from adrenal glands and a known factor to increase magnesium excretion by direct and indirect effects on renal tubular cells. Although the frequency of hypomagnesemia was found to be approximately 5% in adult studies, there is no study in the literature investigating the frequency of hypomagnesemia in children by using fludrocortisone, which has a mineralocorticoid activity. MATERIALS AND METHODS: A multi-center retrospective study was conducted, including children who were under fludrocortisone treatment for primary adrenal insufficiency and applied to participant pediatric endocrinology outpatient clinics. RESULTS: Forty-three patients (58.1% male, 41.9% prepubertal) included in the study, whose median age was 9.18 (0.61-19) years, and the most common diagnosis among the patients was a salt-wasting form of congenital adrenal hyperplasia (67.4%). Mean serum magnesium level was 2.05 (+/-0.13) mg/dL, and hypomagnesemia was not observed in any of the patients treated with fludrocortisone. None of the patients had increased urinary excretion of magnesium. CONCLUSION: Unlike the studies performed in adults, we could not find any evidence of magnesium wasting effect of fludrocortisone treatment with normal or even high doses in children and adolescents. |*Adrenal Hyperplasia, Congenital/blood/diagnosis/drug therapy[MESH] |*Fludrocortisone/administration & dosage/adverse effects[MESH] |*Magnesium Deficiency/diagnosis/etiology/prevention & control[MESH] |*Magnesium/blood/urine[MESH] |Child[MESH] |Drug Monitoring/methods[MESH] |Female[MESH] |Humans[MESH] |Ion Transport/drug effects[MESH] |Male[MESH] |Mineralocorticoids/administration & dosage/adverse effects[MESH] |Renal Elimination/drug effects[MESH] |Retrospective Studies[MESH] |Risk Assessment[MESH]Does fludrocortisone treatment cause hypomagnesemia in children with p(epmc).pdf DeepDyve Pubget Overpricing