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10.1001/jamainternmed.2020.6466

http://scihub22266oqcxt.onion/10.1001/jamainternmed.2020.6466
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33165560!7653540!33165560
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suck abstract from ncbi


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pmid33165560      JAMA+Intern+Med 2021 ; 181 (2): 229-236
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  • Association Between Nursing Home Crowding and COVID-19 Infection and Mortality in Ontario, Canada #MMPMID33165560
  • Brown KA; Jones A; Daneman N; Chan AK; Schwartz KL; Garber GE; Costa AP; Stall NM
  • JAMA Intern Med 2021[Feb]; 181 (2): 229-236 PMID33165560show ga
  • IMPORTANCE: Nursing home residents have been disproportionately affected by coronavirus disease 2019 (COVID-19). Prevention recommendations emphasize frequent testing of health care personnel and residents, but additional strategies are needed. OBJECTIVE: To develop a reproducible index of nursing home crowding and determine whether crowding was associated with COVID-19 cases and mortality in the first months of the COVID-19 epidemic. DESIGN, SETTING, AND PARTICIPANTS: This population-based retrospective cohort study included more than 78?000 residents across more than 600 nursing homes in Ontario, Canada, and was conducted from March 29 to May 20, 2020. EXPOSURES: The nursing home crowding index equaled the mean number of residents per bedroom and bathroom. MAIN OUTCOMES AND MEASURES: The cumulative incidence of COVID-19 cases confirmed by a validated nucleic acid amplification assay and mortality per 100 residents; the introduction of COVID-19 into a home (>/=1 resident case) was a negative tracer. RESULTS: Of 623 homes in Ontario, we obtained complete information on 618 homes (99%) housing 78?607 residents (women, 54?160 [68.9%]; age >/=85 years, 42?919 [54.6%]). A total of 5218 residents (6.6%) developed COVID-19 infection, and 1452 (1.8%) died of COVID-19 infection as of May 20, 2020. COVID-19 infection was distributed unevenly across nursing homes; 4496 infections (86%) occurred in 63 homes (10%). The crowding index ranged across homes from 1.3 (mainly single-occupancy rooms) to 4.0 (exclusively quadruple occupancy rooms); 308 homes (50%) had a high crowding index (>/=2). Incidence in high crowding index homes was 9.7% vs 4.5% in low crowding index homes (P < .001), while COVID-19 mortality was 2.7% vs 1.3%, respectively (P < .001). The likelihood of COVID-19 introduction did not differ (high = 31.3% vs low = 30.2%; P = .79). After adjustment for regional, nursing home, and resident covariates, the crowding index remained associated with an increased incidence of infection (relative risk [RR] = 1.73, 95% CI, 1.10-2.72) and mortality (RR, 1.69; 95% CI, 0.99-2.87). A propensity score analysis yielded similar conclusions for infection (RR, 2.09; 95% CI, 1.30-3.38) and mortality (RR, 1.83; 95% CI, 1.09-3.08). Simulations suggested that converting all 4-bed rooms to 2-bed rooms would have averted 998 COVID-19 cases (19.1%) and 263 deaths (18.1%). CONCLUSIONS AND RELEVANCE: In this cohort of Canadian nursing homes, crowding was common and crowded homes were more likely to experience larger and deadlier COVID-19 outbreaks.
  • |*Crowding[MESH]
  • |*Nursing Homes[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*mortality[MESH]
  • |Disease Outbreaks[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Incidence[MESH]
  • |Male[MESH]
  • |Ontario/epidemiology[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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  • suck abstract from ncbi

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