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10.1038/s41575-020-00391-4

http://scihub22266oqcxt.onion/10.1038/s41575-020-00391-4
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33257835!7703732!33257835
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suck abstract from ncbi


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pmid33257835      Nat+Rev+Gastroenterol+Hepatol 2021 ; 18 (2): 89-90
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  • Modelling intestinal inflammation and infection using mini-gut organoids #MMPMID33257835
  • Li VSW
  • Nat Rev Gastroenterol Hepatol 2021[Feb]; 18 (2): 89-90 PMID33257835show ga
  • In 2020, major advances to the understanding of gastrointestinal inflammatory and infectious disease have been made using 'mini-gut' organoids. Key findings include the discovery of somatic inflammatory gene mutations in ulcerative colitis epithelium, a unique mutational signature in colorectal cancer caused by genotoxic Escherichia coli, and infection of intestinal organoids by SARS-CoV-2.
  • |COVID-19/genetics[MESH]
  • |Colitis, Ulcerative/*genetics/microbiology/physiopathology[MESH]
  • |Colorectal Neoplasms/*genetics/microbiology/physiopathology[MESH]
  • |Escherichia coli Infections/genetics/physiopathology[MESH]
  • |Escherichia coli/isolation & purification[MESH]
  • |Humans[MESH]
  • |Infections/*genetics/virology[MESH]
  • |Inflammation/*genetics/virology[MESH]
  • |Interleukin-17/genetics[MESH]
  • |Intestines/*physiopathology[MESH]
  • |Models, Biological[MESH]
  • |Mutation[MESH]
  • |Organoids/*physiopathology[MESH]


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