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10.1002/ehf2.13139 http://scihub22266oqcxt.onion/10.1002/ehf2.13139 33295126!7835610!33295126     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33295126.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       ESC+Heart+Fail 2021 ; 8 (1): 204-221 Nephropedia Template TP {{tp|p=33295126|t=2021. Time-sensitive approach in the management of acute heart failure |pdf=|usr=}}{{33295126}} gab.com Text Time-sensitive approach in the management of acute heart failure JO: ESC Heart Fail http://www.kidney.de/pget.php?&tw=1&pmid=33295126 #FOAvip Acute heart failure (AHF) has become a global public health burden largely because of the associated high morbidity, mortality, and cost. The treatment options for AHF have remained relatively unchanged over the past decades. Historically, clinical congestion alone has been considered the main target for treatment of acute decompensation in patients with AHF; however, this is an oversimplification of the complex pathophysiology. Within the similar clinical presentation of congestion, significant differences in pathophysiological mechanisms exist between the fluid accumulation and redistribution. Tissue hypoperfusion is another vital characteristic of AHF and should be promptly treated with appropriate interventions. In addition, recent clinical trials of novel therapeutic strategies have shown that heart failure management is 'time sensitive' and suggested that treatment selection based on individual aetiologies, triggers, and risk factor profiles could lead to better outcomes. In this review, we aim to describe the specifics of the 'time-sensitive' approach by the clinical phenotypes, for example, pulmonary/systemic congestion and tissue hypoperfusion, wherein patients are classified based on pathophysiological conditions. This mechanistic classification, in parallel with the comprehensive risk assessment, has become a cornerstone in the management of patients with AHF and thus supports effective decision making by clinicians. We will also highlight how therapeutic modalities should be individualized according to each clinical phenotype. Twit Text FOAVip Time-sensitive approach in the management of acute heart failure ????ESC Heart Fail http://www.kidney.de/pget.php?&tw=1&pmid=33295126 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33295126 #FOAvip English Wikipedia <ref>{{Cite pmid|33295126}}</ref> Time-sensitive approach in the management of acute heart failure #MMPMID33295126 Shiraishi Y; Kawana M; Nakata J; Sato N; Fukuda K; Kohsaka S ESC Heart Fail 2021[Feb]; 8 (1): 204-221 PMID33295126show ga Acute heart failure (AHF) has become a global public health burden largely because of the associated high morbidity, mortality, and cost. The treatment options for AHF have remained relatively unchanged over the past decades. Historically, clinical congestion alone has been considered the main target for treatment of acute decompensation in patients with AHF; however, this is an oversimplification of the complex pathophysiology. Within the similar clinical presentation of congestion, significant differences in pathophysiological mechanisms exist between the fluid accumulation and redistribution. Tissue hypoperfusion is another vital characteristic of AHF and should be promptly treated with appropriate interventions. In addition, recent clinical trials of novel therapeutic strategies have shown that heart failure management is 'time sensitive' and suggested that treatment selection based on individual aetiologies, triggers, and risk factor profiles could lead to better outcomes. In this review, we aim to describe the specifics of the 'time-sensitive' approach by the clinical phenotypes, for example, pulmonary/systemic congestion and tissue hypoperfusion, wherein patients are classified based on pathophysiological conditions. This mechanistic classification, in parallel with the comprehensive risk assessment, has become a cornerstone in the management of patients with AHF and thus supports effective decision making by clinicians. We will also highlight how therapeutic modalities should be individualized according to each clinical phenotype. |*Heart Failure/therapy[MESH] |Acute Disease[MESH] |Humans[MESH] |Morbidity[MESH] |Risk Assessment[MESH]Time-sensitive approach in the management of acute heart failure (epmc).pdf DeepDyve Pubget Overpricing