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10.1080/17474124.2021.1868298

http://scihub22266oqcxt.onion/10.1080/17474124.2021.1868298
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33350352!ä!33350352

suck abstract from ncbi


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pmid33350352      Expert+Rev+Gastroenterol+Hepatol 2021 ; 15 (6): 657-664
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  • Long-term effects of appendectomy in humans: is it the optimal management of appendicitis? #MMPMID33350352
  • Song MY; Ullah S; Yang HY; Ahmed MR; Saleh AA; Liu BR
  • Expert Rev Gastroenterol Hepatol 2021[Jun]; 15 (6): 657-664 PMID33350352show ga
  • INTRODUCTION: Appendectomy remains the gold standard for treating uncomplicated and complicated appendicitis. However, the vermiform appendix may play a significant role in the immune system (secondary immune function) and maintain a reservoir of the normal microbiome for the human body. The aim of this study was to summarize the long-term effects after appendectomy and discuss whether appendectomy is suitable for all appendicitis patients. AREAS COVERED: A comprehensive and unbiased literature search was performed in PubMed. The terms 'appendix,' 'appendicitis,' 'appendectomy,' and 'endoscopic retrograde appendicitis therapy' were searched in the title and/or abstract. This review summarizes the long-term effects of appendectomy on some diseases in humans and describes three methods including appendectomy, medical treatment, and an 'organ-sparing' technique, named endoscopic retrograde appendicitis therapy (ERAT) to treat appendicitis. EXPERT OPINION: Appendectomy remains the first-line therapy for appendicitis. The patient's problem is appendix, not appendicitis. If we treat appendicitis, the problem should be resolved. During COVID-19, an initial antibiotic treatment of mild appendicitis represents a promising strategy. For patients who are worried about the long-term adverse effect after appendectomy and have a strong desire to preserve the appendix and are aware of the risk of appendicitis recurrence, medical treatment, or ERAT could be proposed.
  • |Anti-Bacterial Agents/therapeutic use[MESH]
  • |Appendectomy/*adverse effects[MESH]
  • |Appendicitis/drug therapy/etiology/*surgery[MESH]
  • |COVID-19/epidemiology/*prevention & control/transmission[MESH]
  • |Endoscopy[MESH]
  • |Humans[MESH]
  • |Patient Selection[MESH]


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