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10.1515/jbcpp-2020-0208 http://scihub22266oqcxt.onion/10.1515/jbcpp-2020-0208 33578506!�!33578506 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33578506&cmd=llinks): Failed to open stream: HTTP request failed! 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Therapeutic clinical trials to combat COVID-19 pandemic in India: analysis from trial registry |pdf=|usr=}}{{33578506}} gab.com Text Therapeutic clinical trials to combat COVID-19 pandemic in India: analysis from trial registry JO: J Basic Clin Physiol Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33578506 #FOAvip OBJECTIVES: With the emergence of Novel corona virus, hunt for finding a preventive and therapeutic treatment options has already begun at a rapid pace with faster clinical development programs. The present study was carried out to give an insight of therapeutic interventional trials registered under clinical trial registry of India (CTRI) for COVID-19 pandemic. METHODS: All trials registered under CTRI were evaluated using keyword "COVID" from its inception till 9th June 2020. Out of which, therapeutic interventional studies were chosen for further analysis. Following information was collected for each trial: type of therapeutic intervention (preventive/therapeutic), treatment given, no. of centers (single center/multicentric), type of institution (government/private), study design (randomized/single-blinded/double-blinded) and sponsors (Government/private). Microsoft Office Excel 2007 was used for tabulation and analysis. RESULTS: The search yielded total of 205 trials, out of which, 127 (62%) trials were interventional trials. Out of these, 71 (56%) were AYUSH interventions, 36 (28.3%) tested drugs, 9 (7%) tested a nondrug intervention, rest were nutraceuticals and vaccines. About 66 (56%) were therapeutic trials. Majority were single-centered trials, i.e. 87 (73.7%). Trials were government funded in 57 (48.3%) studies. Majority were randomized controlled trials, i.e. 67 (56.8%). AYUSH preparations included AYUSH-64, Arsenic Album, SamshamaniVati etc. CONCLUSIONS: The number of therapeutic interventional clinical trials was fair in India. A clear-cut need exists for an increase in both quantity and quality of clinical trials for COVID-19. Drug repurposing approach in all systems of medicine can facilitate prompt clinical decisions at lower costs than de novo drug development. Twit Text FOAVip Therapeutic clinical trials to combat COVID-19 pandemic in India: analysis from trial registry ????J Basic Clin Physiol Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33578506 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33578506 #FOAvip English Wikipedia <ref>{{Cite pmid|33578506}}</ref> Therapeutic clinical trials to combat COVID-19 pandemic in India: analysis from trial registry #MMPMID33578506 Batta A; Khirasaria R; Kapoor V; Varshney D J Basic Clin Physiol Pharmacol 2020[Dec]; 32 (3): 267-278 PMID33578506show ga OBJECTIVES: With the emergence of Novel corona virus, hunt for finding a preventive and therapeutic treatment options has already begun at a rapid pace with faster clinical development programs. The present study was carried out to give an insight of therapeutic interventional trials registered under clinical trial registry of India (CTRI) for COVID-19 pandemic. METHODS: All trials registered under CTRI were evaluated using keyword "COVID" from its inception till 9th June 2020. Out of which, therapeutic interventional studies were chosen for further analysis. Following information was collected for each trial: type of therapeutic intervention (preventive/therapeutic), treatment given, no. of centers (single center/multicentric), type of institution (government/private), study design (randomized/single-blinded/double-blinded) and sponsors (Government/private). Microsoft Office Excel 2007 was used for tabulation and analysis. RESULTS: The search yielded total of 205 trials, out of which, 127 (62%) trials were interventional trials. Out of these, 71 (56%) were AYUSH interventions, 36 (28.3%) tested drugs, 9 (7%) tested a nondrug intervention, rest were nutraceuticals and vaccines. About 66 (56%) were therapeutic trials. Majority were single-centered trials, i.e. 87 (73.7%). Trials were government funded in 57 (48.3%) studies. Majority were randomized controlled trials, i.e. 67 (56.8%). AYUSH preparations included AYUSH-64, Arsenic Album, SamshamaniVati etc. CONCLUSIONS: The number of therapeutic interventional clinical trials was fair in India. A clear-cut need exists for an increase in both quantity and quality of clinical trials for COVID-19. Drug repurposing approach in all systems of medicine can facilitate prompt clinical decisions at lower costs than de novo drug development. |*Registries[MESH] |COVID-19/diagnosis/*epidemiology/*therapy[MESH] |Clinical Trials as Topic/*methods[MESH] |Drug Repositioning/methods[MESH] |Humans[MESH] |India/epidemiology[MESH] |Pandemics/prevention & control[MESH]Therapeutic clinical trials to combat COVID-19 pandemic in India: anal(epmc).pdf DeepDyve Pubget Overpricing