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10.1038/s41392-021-00552-0 http://scihub22266oqcxt.onion/10.1038/s41392-021-00552-0 33790236!8009924!33790236     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33790236.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Signal+Transduct+Target+Ther 2021 ; 6 (1): 136 Nephropedia Template TP {{tp|p=33790236|t=2021. Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster |pdf=|usr=}}{{33790236}} gab.com Text Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster JO: Signal Transduct Target Ther http://www.kidney.de/pget.php?&tw=1&pmid=33790236 #FOAvip Epidemiological studies of the COVID-19 patients have suggested the male bias in outcomes of lung illness. To experimentally demonstrate the epidemiological results, we performed animal studies to infect male and female Syrian hamsters with SARS-CoV-2. Remarkably, high viral titer in nasal washings was detectable in male hamsters who presented symptoms of weight loss, weakness, piloerection, hunched back and abdominal respiration, as well as severe pneumonia, pulmonary edema, consolidation, and fibrosis. In contrast with the males, the female hamsters showed much lower shedding viral titers, moderate symptoms, and relatively mild lung pathogenesis. The obvious differences in the susceptibility to SARS-CoV-2 and severity of lung pathogenesis between male and female hamsters provided experimental evidence that SARS-CoV-2 infection and the severity of COVID-19 are associated with gender. Twit Text FOAVip Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster ????Signal Transduct Target Ther http://www.kidney.de/pget.php?&tw=1&pmid=33790236 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33790236 #FOAvip English Wikipedia <ref>{{Cite pmid|33790236}}</ref> Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster #MMPMID33790236 Yuan L; Zhu H; Zhou M; Ma J; Chen R; Chen Y; Chen L; Wu K; Cai M; Hong J; Li L; Liu C; Yu H; Zhang Y; Wang J; Zhang T; Ge S; Zhang J; Yuan Q; Chen Y; Tang Q; Chen H; Cheng T; Guan Y; Xia N Signal Transduct Target Ther 2021[Mar]; 6 (1): 136 PMID33790236show ga Epidemiological studies of the COVID-19 patients have suggested the male bias in outcomes of lung illness. To experimentally demonstrate the epidemiological results, we performed animal studies to infect male and female Syrian hamsters with SARS-CoV-2. Remarkably, high viral titer in nasal washings was detectable in male hamsters who presented symptoms of weight loss, weakness, piloerection, hunched back and abdominal respiration, as well as severe pneumonia, pulmonary edema, consolidation, and fibrosis. In contrast with the males, the female hamsters showed much lower shedding viral titers, moderate symptoms, and relatively mild lung pathogenesis. The obvious differences in the susceptibility to SARS-CoV-2 and severity of lung pathogenesis between male and female hamsters provided experimental evidence that SARS-CoV-2 infection and the severity of COVID-19 are associated with gender. |*COVID-19/metabolism/pathology[MESH] |*Sex Characteristics[MESH] |Animals[MESH] |Disease Models, Animal[MESH] |Disease Susceptibility[MESH] |Female[MESH] |Male[MESH] |Mesocricetus[MESH]Gender associates with both susceptibility to infection and pathogenes(epmc).pdf DeepDyve Pubget Overpricing