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10.1093/trstmh/trab039

http://scihub22266oqcxt.onion/10.1093/trstmh/trab039
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33822232!8083559!33822232
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suck abstract from ncbi


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pmid33822232      Trans+R+Soc+Trop+Med+Hyg 2021 ; 115 (5): 538-550
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  • Research priorities for control of zoonoses in South Africa #MMPMID33822232
  • Simpson G; Quesada F; Chatterjee P; Kakkar M; Chersich MF; Thys S
  • Trans R Soc Trop Med Hyg 2021[May]; 115 (5): 538-550 PMID33822232show ga
  • BACKGROUND: Zoonoses pose major threats to the health of humans, domestic animals and wildlife, as seen in the COVID-19 pandemic. Zoonoses are the commonest source of emerging human infections and inter-species transmission is facilitated by anthropogenic factors such as encroachment and destruction of wilderness areas, wildlife trafficking and climate change. South Africa was selected for a 'One Health' study to identify research priorities for control of zoonoses due to its complex disease burden and an overstretched health system. METHODS: A multidisciplinary group of 18 experts identified priority zoonotic diseases, knowledge gaps and proposed research priorities for the next 5 y. Each priority was scored using predefined criteria by another group of five experts and then weighted by a reference group (n=28) and the 18 experts. RESULTS: Seventeen diseases were mentioned with the top five being rabies (14/18), TB (13/18), brucellosis (11/18), Rift Valley fever (9/11) and cysticercosis (6/18). In total, 97 specific research priorities were listed, with the majority on basic epidemiological research (n=57), such as measuring the burden of various zoonoses (n=24), followed by 20 on development of new interventions. The highest research priority score was for improving existing interventions (0.77/1.0), followed by health policy and systems research (0.72/1.0). CONCLUSION: Future zoonotic research should improve understanding of zoonotic burden and risk factors and new interventions in public health. People with limited rural services, immunocompromised, in informal settlements and high-risk occupations, should be the highest research priority.
  • |*Research[MESH]
  • |Aged[MESH]
  • |Animals[MESH]
  • |COVID-19/epidemiology/*prevention & control[MESH]
  • |Child[MESH]
  • |Cost of Illness[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]
  • |South Africa/epidemiology[MESH]


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