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A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.2174/1389450122666210415100151 http://scihub22266oqcxt.onion/10.2174/1389450122666210415100151 33858312!ä!33858312 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33858312.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Drug+Targets 2022 ; 23 (5): 441-457 Nephropedia Template TP {{tp|p=33858312|t=2022. New Trends in Biological Activities and Clinical Studies of Quinolinic Analogues: A Review |pdf=|usr=}}{{33858312}} gab.com Text New Trends in Biological Activities and Clinical Studies of Quinolinic Analogues: A Review JO: Curr Drug Targets http://www.kidney.de/pget.php?&tw=1&pmid=33858312 #FOAvip The quinolinic ring, present in several molecules, possesses a great diversity of biological activities. Therefore, this ring is in the structural composition of several candidates of drugs in preclinical and clinical studies; thus, it is necessary to compile these results to facilitate the design of new drugs. For this reason, some of the activities of compounds are selected to examine in this review, such as antimalarial, antimicrobial, anticancer, anti-inflammatory, antidiabetic, anti-rheumatic, and antiviral activities. All publications of scientific articles chosen are dated between 2000 and 2020. In addition to presenting the structures of some natural and synthetic compounds with their activities, we have listed the clinical studies of phases III and IV on antimalarial drugs containing the quinoline nucleus and phase III clinical studies on hydroxychloroquine and chloroquine to assess their possible role in COVID-19. Finally, we have reviewed some of the mechanisms of action, as well as the side effects of some of the quinolinic derivatives. Twit Text FOAVip New Trends in Biological Activities and Clinical Studies of Quinolinic Analogues: A Review ????Curr Drug Targets http://www.kidney.de/pget.php?&tw=1&pmid=33858312 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33858312 #FOAvip English Wikipedia <ref>{{Cite pmid|33858312}}</ref> New Trends in Biological Activities and Clinical Studies of Quinolinic Analogues: A Review #MMPMID33858312 da Silva SEB; da Silva Moura JA; de Sousa Nunes TR; da Rocha Pitta I; da Rocha Pitta MG Curr Drug Targets 2022[]; 23 (5): 441-457 PMID33858312show ga The quinolinic ring, present in several molecules, possesses a great diversity of biological activities. Therefore, this ring is in the structural composition of several candidates of drugs in preclinical and clinical studies; thus, it is necessary to compile these results to facilitate the design of new drugs. For this reason, some of the activities of compounds are selected to examine in this review, such as antimalarial, antimicrobial, anticancer, anti-inflammatory, antidiabetic, anti-rheumatic, and antiviral activities. All publications of scientific articles chosen are dated between 2000 and 2020. In addition to presenting the structures of some natural and synthetic compounds with their activities, we have listed the clinical studies of phases III and IV on antimalarial drugs containing the quinoline nucleus and phase III clinical studies on hydroxychloroquine and chloroquine to assess their possible role in COVID-19. Finally, we have reviewed some of the mechanisms of action, as well as the side effects of some of the quinolinic derivatives. |*Antimalarials/pharmacology/therapeutic use[MESH] |*COVID-19 Drug Treatment[MESH] |*Quinolines[MESH] |Chloroquine/pharmacology[MESH] |Humans[MESH]New Trends in Biological Activities and Clinical Studies of Quinolinic(epmc).pdf DeepDyve Pubget Overpricing