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10.33314/jnhrc.v19i1.3373

http://scihub22266oqcxt.onion/10.33314/jnhrc.v19i1.3373
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33934150!ä!33934150

suck abstract from ncbi


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pmid33934150      J+Nepal+Health+Res+Counc 2021 ; 19 (1): 148-153
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  • Ethical Characteristics of Research Proposals Related to COVID-19 Pandemic in Nepal: A Retrospective Review #MMPMID33934150
  • Ghimire N; Hamal PK; Panthee A; Vaidya A; Khadka M; Mahato NK; Karn MK; Verma S; Dhimal M; Ghimire P; Gyanwali P
  • J Nepal Health Res Counc 2021[Apr]; 19 (1): 148-153 PMID33934150show ga
  • BACKGROUND: Public health emergency is vulnerable time where maintaining ethical principles is obligatory while doing research, on the other hand, it is the same time when breach in ethics is much likely whenever a researcher is unaware, unprepared or hastens to do research. The aim of this study was to assess ethical issues of the coronavirus disease 2019 (COVID-19) related research proposals submitted during the early stages of pandemic in Nepal. METHODS: Retrospective analysis of COVID-19 related research proposals and their informed consent document submitted to the ethical review board at Nepal Health Research Council was done for the study. The analysis was done as per the National Ethical Guidelines, Standard Operating Procedure for Health Research in Nepal and World Health Organization guidelines for infectious disease outbreak, 2016 under ethically relevant headings. Descriptive data were analyzed in SPSS v24. RESULTS: The major issues were observed in the informed consent documents where 55% were lacking principal investigator's contact information, 68% not having participant selection criteria, 70% without clear informed consent taking process, 57% without explanation of possible risks. Similarly, 68% of the interventional studies' consent form didn't mention possible adverse events and mitigation mechanisms. CONCLUSIONS: Most of the research proposals related to COVID-19 were devoid of major ethical elements which took longer time for receiving approval and eventually delayed the opportunity for evidence generation in critical time. More attention is needed to increase awareness and to develop capacity of researchers, reviewers, ethics committees and relevant stakeholders at the time of health emergencies.
  • |*Ethical Review[MESH]
  • |Biomedical Research/*ethics[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Humans[MESH]
  • |Nepal/epidemiology[MESH]
  • |Pandemics[MESH]
  • |Research Design[MESH]
  • |Retrospective Studies[MESH]


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