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10.3390/molecules26092620 http://scihub22266oqcxt.onion/10.3390/molecules26092620 33947170!8124705!33947170     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=33947170&cmd=llinks): Failed to open stream: HTTP request failed! 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Metal-Promoted Heterocyclization: A Heterosynthetic Approach to Face a Pandemic Crisis |pdf=|usr=}}{{33947170}} gab.com Text Metal-Promoted Heterocyclization: A Heterosynthetic Approach to Face a Pandemic Crisis JO: Molecules http://www.kidney.de/pget.php?&tw=1&pmid=33947170 #FOAvip The outbreak of SARS-CoV-2 has drastically changed our everyday life and the life of scientists from all over the world. In the last year, the scientific community has faced this worldwide threat using any tool available in order to find an effective response. The recent formulation, production, and ongoing administration of vaccines represent a starting point in the battle against SARS-CoV-2, but they cannot be the only aid available. In this regard, the use of drugs capable to mitigate and fight the virus is a crucial aspect of the pharmacological strategy. Among the plethora of approved drugs, a consistent element is a heterocyclic framework inside its skeleton. Heterocycles have played a pivotal role for decades in the pharmaceutical industry due to their high bioactivity derived from anticancer, antiviral, and anti-inflammatory capabilities. In this context, the development of new performing and sustainable synthetic strategies to obtain heterocyclic molecules has become a key focus of scientists. In this review, we present the recent trends in metal-promoted heterocyclization, and we focus our attention on the construction of heterocycles associated with the skeleton of drugs targeting SARS-CoV-2 coronavirus. Twit Text FOAVip Metal-Promoted Heterocyclization: A Heterosynthetic Approach to Face a Pandemic Crisis ????Molecules http://www.kidney.de/pget.php?&tw=1&pmid=33947170 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33947170 #FOAvip English Wikipedia <ref>{{Cite pmid|33947170}}</ref> Metal-Promoted Heterocyclization: A Heterosynthetic Approach to Face a Pandemic Crisis #MMPMID33947170 Rossi FV; Gentili D; Marcantoni E Molecules 2021[Apr]; 26 (9): � PMID33947170show ga The outbreak of SARS-CoV-2 has drastically changed our everyday life and the life of scientists from all over the world. In the last year, the scientific community has faced this worldwide threat using any tool available in order to find an effective response. The recent formulation, production, and ongoing administration of vaccines represent a starting point in the battle against SARS-CoV-2, but they cannot be the only aid available. In this regard, the use of drugs capable to mitigate and fight the virus is a crucial aspect of the pharmacological strategy. Among the plethora of approved drugs, a consistent element is a heterocyclic framework inside its skeleton. Heterocycles have played a pivotal role for decades in the pharmaceutical industry due to their high bioactivity derived from anticancer, antiviral, and anti-inflammatory capabilities. In this context, the development of new performing and sustainable synthetic strategies to obtain heterocyclic molecules has become a key focus of scientists. In this review, we present the recent trends in metal-promoted heterocyclization, and we focus our attention on the construction of heterocycles associated with the skeleton of drugs targeting SARS-CoV-2 coronavirus. |*COVID-19 Drug Treatment[MESH] |Antiviral Agents/chemical synthesis/chemistry/*pharmacology[MESH] |COVID-19/virology[MESH] |Catalysis[MESH] |Chemistry Techniques, Synthetic/*methods[MESH] |Coronavirus 3C Proteases/antagonists & inhibitors/metabolism[MESH] |Heterocyclic Compounds/chemical synthesis/chemistry/*pharmacology[MESH] |Humans[MESH] |Metals/chemistry[MESH] |Protease Inhibitors/chemical synthesis/chemistry/pharmacology[MESH]Metal-Promoted Heterocyclization: A Heterosynthetic Approach to Face a(epmc).pdf DeepDyve Pubget Overpricing