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10.1038/s41598-021-91265-5

http://scihub22266oqcxt.onion/10.1038/s41598-021-91265-5
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suck abstract from ncbi


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pmid34083700      Sci+Rep 2021 ; 11 (1): 11778
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  • Modeling of aerosol transmission of airborne pathogens in ICU rooms of COVID-19 patients with acute respiratory failure #MMPMID34083700
  • Crawford C; Vanoli E; Decorde B; Lancelot M; Duprat C; Josserand C; Jilesen J; Bouadma L; Timsit JF
  • Sci Rep 2021[Jun]; 11 (1): 11778 PMID34083700show ga
  • The COVID-19 pandemic has generated many concerns about cross-contamination risks, particularly in hospital settings and Intensive Care Units (ICU). Virus-laden aerosols produced by infected patients can propagate throughout ventilated rooms and put medical personnel entering them at risk. Experimental results found with a schlieren optical method have shown that the air flows generated by a cough and normal breathing were modified by the oxygenation technique used, especially when using High Flow Nasal Canulae, increasing the shedding of potentially infectious airborne particles. This study also uses a 3D Computational Fluid Dynamics model based on a Lattice Boltzmann Method to simulate the air flows as well as the movement of numerous airborne particles produced by a patient's cough within an ICU room under negative pressure. The effects of different mitigation scenarii on the amount of aerosols potentially containing SARS-CoV-2 that are extracted through the ventilation system are investigated. Numerical results indicate that adequate bed orientation and additional air treatment unit positioning can increase by 40% the number of particles extracted and decrease by 25% the amount of particles deposited on surfaces 45s after shedding. This approach could help lay the grounds for a more comprehensive way to tackle contamination risks in hospitals, as the model can be seen as a proof of concept and be adapted to any room configuration.
  • |*Air Microbiology[MESH]
  • |Aerosols[MESH]
  • |COVID-19/*transmission[MESH]
  • |Cough/*virology[MESH]
  • |Humans[MESH]
  • |Intensive Care Units[MESH]
  • |Models, Theoretical[MESH]
  • |Optical Imaging[MESH]
  • |Respiratory Distress Syndrome/*virology[MESH]


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