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10.2147/COPD.S312493 http://scihub22266oqcxt.onion/10.2147/COPD.S312493 34113088!8184145!34113088     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\34113088.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Int+J+Chron+Obstruct+Pulmon+Dis 2021 ; 16 (ä): 1549-1554 Nephropedia Template TP {{tp|p=34113088|t=2021. Characterization of COPD Admissions During the First COVID-19 Outbreak |pdf=|usr=}}{{34113088}} gab.com Text Characterization of COPD Admissions During the First COVID-19 Outbreak JO: Int J Chron Obstruct Pulmon Dis http://www.kidney.de/pget.php?&tw=1&pmid=34113088 #FOAvip PURPOSE: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and mortality in relation to the presence of COVID-19. PATIENTS AND METHODS: We conducted a case-control study of patients admitted in four teaching hospitals throughout Spain between March 15 and April 30, 2020. Hospital admissions of respiratory cause with and without PCR-proven SARS-CoV-2 infection in patients with COPD were evaluated. Baseline and episode-related clinical characteristics were analyzed. Logistic regression analysis was performed to evaluate the risk for mortality. RESULTS: During the study period, 2101 patients were admitted for respiratory worsening, 1200 (57.1%) with COVID-19. A total of 228 (10.8%) were admitted due to COPD worsening, of whom 52 (22.8%) tested positive for COVID-19. COPD patients with COVID-19, when compared to those without COVID-19, were more frequently males with better lung function (FEV(1) postbronchodilator 71% vs 46% respectively, p<0.001) and had higher mortality (44.9% vs 13.6% respectively, p<0.001) despite similar age, comorbidities, total days of hospitalization and admission to intensive care unit. COVID-19 and eosinopenia were the strongest risk factors for mortality in the multivariate analysis in the overall COPD population. Inhaled corticosteroid use was not associated to mortality. CONCLUSION: Hospitalizations for ECOPD without COVID-19 were more frequent than COPD with COVID-19 during the first outbreak, but the latter were associated with higher mortality and low eosinophil counts that warrant further analysis. Twit Text FOAVip Characterization of COPD Admissions During the First COVID-19 Outbreak ????Int J Chron Obstruct Pulmon Dis http://www.kidney.de/pget.php?&tw=1&pmid=34113088 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=34113088 #FOAvip English Wikipedia <ref>{{Cite pmid|34113088}}</ref> Characterization of COPD Admissions During the First COVID-19 Outbreak #MMPMID34113088 Cosio BG; Shafiek H; Toledo-Pons N; Iglesias A; Barcelo M; Represas-Represas C; Comeche L; Catalan P; Fernandez-Villar A; Lopez-Campos JL; Echave-Sustaeta J; Soler-Cataluna JJ Int J Chron Obstruct Pulmon Dis 2021[]; 16 (ä): 1549-1554 PMID34113088show ga PURPOSE: Exacerbations of COPD (ECOPD) are a frequent cause of hospitalization that seemed to ameliorate during the COVID outbreak. We aimed to evaluate the clinical characteristics of COPD-related hospital admissions and mortality in relation to the presence of COVID-19. PATIENTS AND METHODS: We conducted a case-control study of patients admitted in four teaching hospitals throughout Spain between March 15 and April 30, 2020. Hospital admissions of respiratory cause with and without PCR-proven SARS-CoV-2 infection in patients with COPD were evaluated. Baseline and episode-related clinical characteristics were analyzed. Logistic regression analysis was performed to evaluate the risk for mortality. RESULTS: During the study period, 2101 patients were admitted for respiratory worsening, 1200 (57.1%) with COVID-19. A total of 228 (10.8%) were admitted due to COPD worsening, of whom 52 (22.8%) tested positive for COVID-19. COPD patients with COVID-19, when compared to those without COVID-19, were more frequently males with better lung function (FEV(1) postbronchodilator 71% vs 46% respectively, p<0.001) and had higher mortality (44.9% vs 13.6% respectively, p<0.001) despite similar age, comorbidities, total days of hospitalization and admission to intensive care unit. COVID-19 and eosinopenia were the strongest risk factors for mortality in the multivariate analysis in the overall COPD population. Inhaled corticosteroid use was not associated to mortality. CONCLUSION: Hospitalizations for ECOPD without COVID-19 were more frequent than COPD with COVID-19 during the first outbreak, but the latter were associated with higher mortality and low eosinophil counts that warrant further analysis. |*COVID-19[MESH] |*Pulmonary Disease, Chronic Obstructive/diagnosis/epidemiology/therapy[MESH] |Case-Control Studies[MESH] |Disease Outbreaks[MESH] |Hospitalization[MESH] |Humans[MESH] |Male[MESH] |SARS-CoV-2[MESH]Characterization of COPD Admissions During the First COVID-19 Outbreak(epmc).pdf DeepDyve Pubget Overpricing