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suck abstract from ncbi


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pmid34121304      J+Cosmet+Dermatol 2021 ; 20 (8): 2396-2408
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  • Virgin coconut oil as prophylactic therapy against alcohol damage on skin in COVID times #MMPMID34121304
  • Saraogi P; Kaushik V; Chogale R; Chavan S; Gode V; Mhaskar S
  • J Cosmet Dermatol 2021[Aug]; 20 (8): 2396-2408 PMID34121304show ga
  • BACKGROUND: Increased frequency of using alcohol-based hand sanitizers (ABHS) by consumers during COVID times have resulted in increased incidences of skin issues on palms. OBJECTIVE: (1) To quantify skin damage with increased usage frequency of ABHS by consumers and (2) To evaluate Virgin Coconut Oil (VCO) as natural prophylactic agent to counter the adverse effects. METHODS: In-home usage study was carried out with 60 volunteers for a 15-day intervention-Control Group: 6 applications per day of ABHS and Test Group: Overnight VCO use (6-8 drops) followed by 6x usage per day of ABHS. This leg included dermatological evaluation and WHO Self-Assessment Scale for skin health. Another leg of measurement included non-invasive instrumental study (Moisture & TEWL Probes, Tape Strip for protein content and IR spectroscopy for protein & lipid content) on forearm of 12 subjects (25-60 years age) with and without VCO application and repeated alcohol exposure. RESULTS: In-home usage study established consumer experiencing skin protective effect of VCO in the context of ABHS onslaught. 25% increase in perceived moisture content was recorded for VCO users, using WHO Self-Assessment Scale. Instrumental studies confirmed an increase in TEWL and decrease in lipids & protein content. Overnight VCO application resists the extraction which builds up with repeated application. CONCLUSIONS: Current work provides evidence of compromised hand skin barrier with ABHS daily usage. Overnight VCO application helps prepare the skin for next day alcohol use. Based on the findings, a regimen of overnight VCO application on hands as a natural prophylactic is recommended.
  • |*COVID-19[MESH]
  • |Coconut Oil[MESH]
  • |Ethanol[MESH]
  • |Humans[MESH]
  • |Lipids[MESH]


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