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10.1111/all.14767

http://scihub22266oqcxt.onion/10.1111/all.14767
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34152613!8014537!34152613
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suck abstract from ncbi


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pmid34152613      Allergy 2021 ; 76 (6): 1813-1824
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  • Management of patients with atopic dermatitis undergoing systemic therapy during COVID-19 pandemic in Italy: Data from the DA-COVID-19 registry #MMPMID34152613
  • Chiricozzi A; Talamonti M; De Simone C; Galluzzo M; Gori N; Fabbrocini G; Marzano AV; Girolomoni G; Offidani A; Rossi MT; Bianchi L; Cristaudo A; Fierro MT; Stingeni L; Pellacani G; Argenziano G; Patrizi A; Pigatto P; Romanelli M; Savoia P; Rubegni P; Foti C; Milanesi N; Belloni Fortina A; Bongiorno MR; Grieco T; Di Nuzzo S; Fargnoli MC; Carugno A; Motolese A; Rongioletti F; Amerio P; Balestri R; Potenza C; Micali G; Patruno C; Zalaudek I; Lombardo M; Feliciani C; Di Nardo L; Guarneri F; Peris K
  • Allergy 2021[Jun]; 76 (6): 1813-1824 PMID34152613show ga
  • BACKGROUND: Few and small studies have described the management of immunomodulant/immunosuppressive therapies or phototherapy in atopic dermatitis (AD) patients during coronavirus disease 2019 (COVID-19) pandemic. METHODS: A national registry, named DA-COVID-19 and involving 35 Italian dermatology units, was established in order to evaluate the impact of COVID-19 pandemic on the management of adult AD patients treated with systemic immunomodulant/immunosuppressive medications or phototherapy. Demographic and clinical data were obtained at different timepoints by teledermatology during COVID-19 pandemic, when regular visits were not allowed due to sanitary restrictions. Disease severity was assessed by both physician- and patient-reported assessment scores evaluating itch intensity, sleep disturbances, and AD severity. RESULTS: A total of 1831 patients were included, with 1580/1831 (86.3%) continuing therapy during pandemic. Most patients were treated with dupilumab (86.1%, 1576/1831) that was interrupted in only 9.9% (156/1576) of cases, while systemic immunosuppressive compounds were more frequently withdrawn. Treatment interruption was due to decision of the patient, general practitioner, or dermatologist in 39.9% (114/286), 5.6% (16/286), and 30.1% (86/286) of cases, respectively. Fear of increased susceptibility to SARS-CoV-2 infection (24.8%, 71/286) was one of the main causes of interruption. Sixteen patients (0.9%) resulted positive to SARS-CoV-2 infection; 3 of them (0.2%) were hospitalized but no cases of COVID-related death occurred. CONCLUSIONS: Most AD patients continued systemic treatments during COVID pandemic and lockdown period, without high impact on disease control, particularly dupilumab-treated patients.
  • |*COVID-19[MESH]
  • |*Dermatitis, Atopic/drug therapy/epidemiology[MESH]
  • |Adult[MESH]
  • |Communicable Disease Control[MESH]
  • |Humans[MESH]
  • |Italy/epidemiology[MESH]
  • |Pandemics[MESH]
  • |Registries[MESH]


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