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10.1111/sdi.12997

http://scihub22266oqcxt.onion/10.1111/sdi.12997
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suck abstract from ncbi


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pmid34169574      Semin+Dial 2021 ; 34 (5): 338-346
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  • Aftermath of fortnightly universal testing for severe acute respiratory corona virus-2 infection in maintenance hemodialysis patients #MMPMID34169574
  • Patel MR; Kushwaha RS; Behera M; Bhadauria DS; Yachha M; Kaul A; Prasad N
  • Semin Dial 2021[Sep]; 34 (5): 338-346 PMID34169574show ga
  • INTRODUCTION: Asymptomatic maintenance hemodialysis patients with acute respiratory corona virus-2 (SARS-COV-2) are missed with pre-dialysis screening without testing. The possible ideal strategy of testing each patient before each shift with reverse transcription polymerase chain reaction (RT-PCR) is not feasible. We aimed to study the effectiveness of fortnightly screening with RT-PCR for SARS-CoV-2 in curbing transmission. METHODS: Between July 1, 2020 and September 30, 2020, all 273 patients receiving hemodialysis were subjected to fortnightly testing for SARS-Cov-2 in the unit to detect asymptomatic patients. The cost and effectiveness of universal testing in preventing transmission were analyzed using susceptible-infectious-removed (SIR) modeling assuming R(0) of 2.2. RESULTS: Of 273 MHD patients, 55 (20.1%) found infected with SARS-CoV-2 over 3 months. Six (10.9%) were symptomatic, and 49 (89.1%) asymptomatic at the time of testing. Six (10.9%) asymptomatic patients develop symptoms later, and 43 (78.2%) remained asymptomatic. A total of seven (6.1%) HCWs also tested positive for the virus. Fortnightly universal testing is cost-effective, and SIR modeling proved effective in preventing person-to-person transmission. CONCLUSIONS: Repeated universal testing in maintenance hemodialysis patients detected 89% of asymptomatic SARS-CoV-2 patients over 3 months and appeared to be an effective strategy to prevent person-to-person transmission in the dialysis unit.
  • |*COVID-19 Testing[MESH]
  • |*Mass Screening[MESH]
  • |*Renal Dialysis[MESH]
  • |Adult[MESH]
  • |Asymptomatic Diseases[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |India[MESH]
  • |Male[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]


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