
| 10.12688/wellcomeopenres.15796.2
http://scihub22266oqcxt.onion/10.12688/wellcomeopenres.15796.2
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Wellcome+Open+Res 2020 ; 5 (�): 98 Nephropedia Template TP
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Hand Hygiene Practices and the Risk of Human Coronavirus Infections in a UK Community Cohort #MMPMID34250260Beale S; Johnson AM; Zambon M; Hayward AC; Fragaszy EBWellcome Open Res 2020[]; 5 (�): 98 PMID34250260show ga
Background: Hand hygiene may mitigate the spread of COVID-19 in community settings; however, empirical evidence is limited. Given reports of similar transmission mechanisms for COVID-19 and seasonal coronaviruses, we investigated whether hand hygiene impacted the risk of acquiring seasonal coronavirus infections. Methods: Data were drawn from three successive winter cohorts (2006-2009) of the England-wide Flu Watch study. Participants ( n=1633) provided baseline estimates of hand hygiene behaviour. Coronavirus infections were identified from nasal swabs using RT-PCR. Poisson mixed models estimated the effect of hand hygiene on personal risk of coronavirus illness, both unadjusted and adjusted for confounding by age and healthcare worker status. Results: Moderate-frequency handwashing (6-10 times per day) predicted a lower personal risk of coronavirus infection (adjusted incidence rate ratio (aIRR) =0.64, p=0.04). There was no evidence for a dose-response effect of handwashing, with results for higher levels of hand hygiene (>10 times per day) not significant (aIRR =0.83, p=0.42). Conclusions: This is the first empirical evidence that regular handwashing can reduce personal risk of acquiring seasonal coronavirus infection. These findings support clear public health messaging around the protective effects of hand washing in the context of the current COVID-19 pandemic.�
  
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