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10.1080/00015385.2021.1967614

http://scihub22266oqcxt.onion/10.1080/00015385.2021.1967614
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34427169!ä!34427169

suck abstract from ncbi


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pmid34427169      Acta+Cardiol 2022 ; 77 (8): 720-728
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  • Is the revascularisation strategy and outcome different in patients with acute coronary syndrome in COVID-19 pandemic era: a tertiary centre experience #MMPMID34427169
  • Akturk IF; Yildiz C; Karabulut D; Oflar E; Sahin A; Ertugrul AS; Koyuncu A; Polat V; Karahan A; Kosar F; Alp IB; Keskin K; Caglar FNT
  • Acta Cardiol 2022[Oct]; 77 (8): 720-728 PMID34427169show ga
  • BACKGROUND: In this study, we aimed to compare the management and clinical outcomes of patients with acute coronary syndrome (ACS) before and during pandemic. METHODS: A total of 239 patients with ACS were enrolled into the study. Patients who were admitted during pandemic were compared with pre-pandemic patients according to their demographic, biochemical, angiographic features, revascularisation strategies and clinical outcomes. RESULTS: During the pandemic period, we observed an increase in total number of patient with ST elevation myocardial infarction patients compared to the pre-pandemic period. Initial high sensitive troponin and CK-MB levels were statistically higher in the pandemic group patients (1953 pg/ml versus 259 pg/ml for troponin I and 14 ng/ml versus 6 ng/ml for CK-MB p < 0.0001, p = 0.02, respectively). Type 4a myocardial infarction due to stent thrombosis was more frequent in pandemic group relative to the pre-pandemic group (10 versus 0, p = 0.003). Post-procedural TIMI flow grade was lower in the pandemic group and distal embolisation and TIMI thrombus score were significantly higher in the pandemic group compared to the pre-pandemic group (p = 0.001, p = 0.02, and p = 0.002, respectively). The number of patients who underwent bypass surgery was much lower compared to pre-pandemic period (27 versus 8, p < 0.0001). There was no statistically significant difference in hospital mortality and short-term all-cause mortality among groups (p > 0.05). CONCLUSION: Although clinical, laboratory, and angiographic features were worse in ACS patients during pandemic, the mortality rate of ACS was similar in both pre-pandemic and pandemic era. It is important to keep coronary intensive care units and catheter labs open and fully-functioning during the pandemic.
  • |*Acute Coronary Syndrome/diagnosis/epidemiology/surgery[MESH]
  • |*COVID-19/epidemiology[MESH]
  • |*Thrombosis[MESH]
  • |Coronary Angiography[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |Treatment Outcome[MESH]


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