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A real-world study of immune thrombocytopenia management during the COVID-19 pandemic in the UK #MMPMID34448203
Rampotas A; Watson E; Burton K; Hill QA; Pavord S
Br J Haematol 2022[Jan]; 196 (2): 351-355 PMID34448203show ga
The COVID-19 pandemic has created many challenges in the management of immune thrombocytopenic purpura (ITP). The recommendation for avoidance of steroids by WHO led to the off-licence use, supported by NHS England, of thrombopoietin mimetics (TPO-RA) for newly diagnosed or relapsed ITP. This is a real-world prospective study which investigated the treatment patterns and outcomes in this setting. Twenty-four hospitals across the UK submitted 343 cases. Corticosteroids remain the mainstay of ITP treatment, but TPO-RAs were more effective. Incidental COVID-19 infection was identified in a significant number of patients (9.5%), while 14 cases were thought to be secondary to COVID-19 vaccination.