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10.3389/fimmu.2021.801797 http://scihub22266oqcxt.onion/10.3389/fimmu.2021.801797 35003130!8733294!35003130     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=35003130&cmd=llinks): Failed to open stream: HTTP request failed! 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Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies |pdf=|usr=}}{{35003130}} gab.com Text Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies JO: Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35003130 #FOAvip BACKGROUND: Limited data are available regarding the balance of risks and benefits from human milk and/or breastfeeding during and following maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). OBJECTIVE: To investigate whether SARS-CoV-2 can be detected in milk and on the breast after maternal coronavirus disease 2019 (COVID-19) diagnosis; and characterize concentrations of milk immunoglobulin (Ig) A specific to the SARS-CoV-2 spike glycoprotein receptor binding domain (RBD) during the 2 months after onset of symptoms or positive diagnostic test. METHODS: Using a longitudinal study design, we collected milk and breast skin swabs one to seven times from 64 lactating women with COVID-19 over a 2-month period, beginning as early as the week of diagnosis. Milk and breast swabs were analyzed for SARS-CoV-2 RNA, and milk was tested for anti-RBD IgA. RESULTS: SARS-CoV-2 was not detected in any milk sample or on 71% of breast swabs. Twenty-seven out of 29 (93%) breast swabs collected after breast washing tested negative for SARS-CoV-2. Detection of SARS-CoV-2 on the breast was associated with maternal coughing and other household COVID-19. Most (75%; 95% CI, 70-79%; n=316) milk samples contained anti-RBD IgA, and concentrations increased (P=.02) during the first two weeks following onset of COVID-19 symptoms or positive test. Milk-borne anti-RBD IgA persisted for at least two months in 77% of women. CONCLUSION: Milk produced by women with COVID-19 does not contain SARS-CoV-2 and is likely a lasting source of passive immunity via anti-RBD IgA. These results support recommendations encouraging lactating women to continue breastfeeding during and after COVID-19 illness. Twit Text FOAVip Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies ????Front Immunol http://www.kidney.de/pget.php?&tw=1&pmid=35003130 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35003130 #FOAvip English Wikipedia <ref>{{Cite pmid|35003130}}</ref> Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RNA but Has Persistent Levels of SARS-CoV-2-Specific IgA Antibodies #MMPMID35003130 Pace RM; Williams JE; Jarvinen KM; Meehan CL; Martin MA; Ley SH; Barbosa-Leiker C; Andres A; Yeruva L; Belfort MB; Caffe B; Navarrete AD; Lackey KA; Pace CDW; Gogel AC; Fehrenkamp BD; Klein M; Young BE; Rosen-Carole C; Diaz N; Gaw SL; Flaherman V; McGuire MA; McGuire MK; Seppo AE Front Immunol 2021[]; 12 (�): 801797 PMID35003130show ga BACKGROUND: Limited data are available regarding the balance of risks and benefits from human milk and/or breastfeeding during and following maternal infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). OBJECTIVE: To investigate whether SARS-CoV-2 can be detected in milk and on the breast after maternal coronavirus disease 2019 (COVID-19) diagnosis; and characterize concentrations of milk immunoglobulin (Ig) A specific to the SARS-CoV-2 spike glycoprotein receptor binding domain (RBD) during the 2 months after onset of symptoms or positive diagnostic test. METHODS: Using a longitudinal study design, we collected milk and breast skin swabs one to seven times from 64 lactating women with COVID-19 over a 2-month period, beginning as early as the week of diagnosis. Milk and breast swabs were analyzed for SARS-CoV-2 RNA, and milk was tested for anti-RBD IgA. RESULTS: SARS-CoV-2 was not detected in any milk sample or on 71% of breast swabs. Twenty-seven out of 29 (93%) breast swabs collected after breast washing tested negative for SARS-CoV-2. Detection of SARS-CoV-2 on the breast was associated with maternal coughing and other household COVID-19. Most (75%; 95% CI, 70-79%; n=316) milk samples contained anti-RBD IgA, and concentrations increased (P=.02) during the first two weeks following onset of COVID-19 symptoms or positive test. Milk-borne anti-RBD IgA persisted for at least two months in 77% of women. CONCLUSION: Milk produced by women with COVID-19 does not contain SARS-CoV-2 and is likely a lasting source of passive immunity via anti-RBD IgA. These results support recommendations encouraging lactating women to continue breastfeeding during and after COVID-19 illness. |Adult[MESH] |Antibodies, Viral/*analysis/immunology[MESH] |Breast Feeding[MESH] |COVID-19/immunology[MESH] |Female[MESH] |Humans[MESH] |Immunization, Passive[MESH] |Immunoglobulin A/*analysis/immunology[MESH] |Lactation[MESH] |Longitudinal Studies[MESH] |Milk, Human/*immunology/virology[MESH] |RNA, Viral/genetics[MESH]Milk From Women Diagnosed With COVID-19 Does Not Contain SARS-CoV-2 RN(epmc).pdf DeepDyve Pubget Overpricing