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10.1002/adbi.202200006 http://scihub22266oqcxt.onion/10.1002/adbi.202200006 35514065!ä!35514065 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\35514065.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Adv+Biol+(Weinh) 2022 ; 6 (7): e2200006 Nephropedia Template TP {{tp|p=35514065|t=2022. Phase Separation: "The Master Key" to Deciphering the Physiological and Pathological Functions of Cells |pdf=|usr=}}{{35514065}} gab.com Text Phase Separation: "The Master Key" to Deciphering the Physiological and Pathological Functions of Cells JO: Adv Biol (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=35514065 #FOAvip Phase separation is a hot research field at present. It involves almost all aspects of cells and plays a significant role in cells, promising to be "a master key" in unlocking the mysteries of nature. In this review, the factors that affect phase separation are introduced, such as own component, electrostatic interaction, and chemical modification. Furthermore, the physiological roles of phase separation in cells, including molecules transport channel, gene expression and regulation, cellular division and differentiation, stress response, proteins refolding and degradation, cell connections, construction of skin barrier, and cell signals transmission, are highlighted. However, the disorder of phase separation leads to pathological condensates, which are associated with neurodegenerative diseases, tumors, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This relationship is considered the potential target for developing corresponded drugs and therapy. Some drugs targeting phase separation have improved meaningful, such as tankyrase, lipoamide, oligonucleotides, elvitagravir, nilotinib, CVL218, PJ34. All in all, mystery phase separation provides a new viewpoint for researchers to explore cells, and is expected to solve many unknown phenomena in nature. Twit Text FOAVip Phase Separation: "The Master Key" to Deciphering the Physiological and Pathological Functions of Cells ????Adv Biol (Weinh) http://www.kidney.de/pget.php?&tw=1&pmid=35514065 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=35514065 #FOAvip English Wikipedia <ref>{{Cite pmid|35514065}}</ref> Phase Separation: "The Master Key" to Deciphering the Physiological and Pathological Functions of Cells #MMPMID35514065 Wei C; Li M; Li X; Lyu J; Zhu X Adv Biol (Weinh) 2022[Jul]; 6 (7): e2200006 PMID35514065show ga Phase separation is a hot research field at present. It involves almost all aspects of cells and plays a significant role in cells, promising to be "a master key" in unlocking the mysteries of nature. In this review, the factors that affect phase separation are introduced, such as own component, electrostatic interaction, and chemical modification. Furthermore, the physiological roles of phase separation in cells, including molecules transport channel, gene expression and regulation, cellular division and differentiation, stress response, proteins refolding and degradation, cell connections, construction of skin barrier, and cell signals transmission, are highlighted. However, the disorder of phase separation leads to pathological condensates, which are associated with neurodegenerative diseases, tumors, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This relationship is considered the potential target for developing corresponded drugs and therapy. Some drugs targeting phase separation have improved meaningful, such as tankyrase, lipoamide, oligonucleotides, elvitagravir, nilotinib, CVL218, PJ34. All in all, mystery phase separation provides a new viewpoint for researchers to explore cells, and is expected to solve many unknown phenomena in nature. |*COVID-19[MESH] |*Neurodegenerative Diseases/metabolism[MESH] |Cell Division[MESH] |Humans[MESH] |Proteins[MESH]Phase Separation: "The Master Key" to Deciphering the Physiological an(epmc).pdf DeepDyve Pubget Overpricing