Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1152/ajprenal.1984.246.5.F656

http://scihub22266oqcxt.onion/10.1152/ajprenal.1984.246.5.F656
suck pdf from google scholar
6326615!ä!6326615

Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=6326615&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215

suck abstract from ncbi


Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534

Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\6326615.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117
pmid6326615      Am+J+Physiol 1984 ; 246 (5 Pt 2): F656-62
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • Steroid regulation of Na+-K+-ATPase: differential sensitivities along the nephron #MMPMID6326615
  • Rayson BM; Lowther SO
  • Am J Physiol 1984[May]; 246 (5 Pt 2): F656-62 PMID6326615show ga
  • Steroid hormonal activation of the Na+-K+-ATPase enzyme was examined in enriched preparations of outer medullary collecting tubules (MCT) and outer medullary thick ascending limbs of the loop of Henle (MAL), prepared by sedimentation through a discontinuous Ficoll gradient. Using morphological criteria, there was a 2.9-fold enrichment of MCT in fraction 1 when compared with fraction 2 and a 2.2-fold enrichment of MAL in fraction 2 when compared with fraction 1. This separation was further defined using biochemical markers. Na+-K+-ATPase activity, Mg2+-ATPase activity, and the adenylate cyclase response to a number of hormones each supported the morphologic definition of separation. The two preparations were challenged in vitro with both aldosterone and dexamethasone. In fraction 1, the fraction enriched in the MCT, 10(-8) M aldosterone stimulated Na+-K+-ATPase activity by 37%. The same concentration of dexamethasone was without effect. In contrast, 10(-8) M dexamethasone stimulated Na+-K+-ATPase activity by 27% in fraction 2, the fraction enriched in the MAL. In this fraction an equimolar concentration of aldosterone was without effect. Thus, the regulation of Na+-K+-ATPase activity by mineralocorticoids on the one hand and by glucocorticoids on the other would appear to be discontinuously localized along the length of the outer medullary distal nephron.
  • |Adenosine Triphosphatases/metabolism[MESH]
  • |Adenylyl Cyclases/metabolism[MESH]
  • |Aldosterone/pharmacology[MESH]
  • |Animals[MESH]
  • |Cell Survival[MESH]
  • |Dexamethasone/pharmacology[MESH]
  • |Kidney Tubules/enzymology[MESH]
  • |Male[MESH]
  • |Nephrons/cytology/*enzymology[MESH]
  • |Rats[MESH]
  • |Rats, Inbred Strains[MESH]
  • |Sodium-Potassium-Exchanging ATPase/*metabolism[MESH]
  • |Steroids/*physiology[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    Linkout box