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10.1099/0022-1317-74-9-2011

http://scihub22266oqcxt.onion/10.1099/0022-1317-74-9-2011
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8376975!�!8376975

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suck abstract from ncbi


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pmid8376975      J+Gen+Virol 1993 ; 74 ( Pt 9) (�): 2011-4
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  • Trans-activation of the long terminal repeat of human immunodeficiency virus type 1 by the parvovirus B19 NS1 gene product #MMPMID8376975
  • Sol N; Morinet F; Alizon M; Hazan U
  • J Gen Virol 1993[Sep]; 74 ( Pt 9) (�): 2011-4 PMID8376975show ga
  • Persistent parvovirus B19 infections in human immunodeficiency virus type 1 (HIV-1)-infected patients have been reported. The two viruses could share common target cells. The NS1 protein of B19 regulates B19 expression and we have investigated its possible effect on the long terminal repeat (LTR) of HIV-1. In transient transfection experiments, NS1 trans-activated the expression of reporter genes under the control of the HIV-1 LTR. The effect of NS1 was apparent only in the presence of the HIV-1 Tat protein, and required intact TAR and TATA box sequences.
  • |*HIV Long Terminal Repeat[MESH]
  • |*Transcriptional Activation[MESH]
  • |Cell Line[MESH]
  • |Chloramphenicol O-Acetyltransferase/biosynthesis/metabolism[MESH]
  • |Enhancer Elements, Genetic[MESH]
  • |Frameshift Mutation[MESH]
  • |Gene Expression Regulation, Viral[MESH]
  • |Gene Products, tat/metabolism[MESH]
  • |Genes, Viral[MESH]
  • |Genetic Vectors[MESH]
  • |HIV-1/*genetics/metabolism[MESH]
  • |Humans[MESH]
  • |Parvoviridae/genetics/*metabolism[MESH]
  • |Promoter Regions, Genetic[MESH]
  • |Protein Biosynthesis[MESH]
  • |Recombinant Proteins/biosynthesis/metabolism[MESH]
  • |Transcription, Genetic[MESH]
  • |Transfection[MESH]
  • |Viral Nonstructural Proteins/biosynthesis/*metabolism[MESH]


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