
| 10.1152/ajpregu.00176.2014
http://scihub22266oqcxt.onion/10.1152/ajpregu.00176.2014
 C4214833!4214833!24920727
free
free
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Am+J+Physiol+Regul+Integr+Comp+Physiol 2014 ; 307 (5): R490-2 Nephropedia Template TP
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Role of decidual natural killer cells, interleukin-15, and interferon-? in placental development and preeclampsia #MMPMID24920727Sones JL; Lob HE; Isroff CE; Davisson RLAm J Physiol Regul Integr Comp Physiol 2014[Sep]; 307 (5): R490-2 PMID24920727show ga
Preeclampsia is a hypertensive, proteinuric disease that affects 5?10% of all pregnancies and is a leading cause of maternal and perinatal morbidity/mortality (Soto et al., J Matern Fetal Neonatal Med 25: 498?507, 2011). The primary treatment for preeclampsia still is delivery of the fetus and placenta. The underlying mechanisms remain elusive. One possibility is inadequate uterine angiogenesis/vascularity (decidualization) at the time of implantation (Torry et al., Am J Reprod Immunol 51: 257?268, 2004). Here, we review evidence for dysregulation of decidual natural killer (dNK) cells, which secrete important angiogenic factors during decidualization, as a contributing factor in preeclampsia.�
  
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