
| 10.1111/ajt.12735
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 C4274784!4274784!24934732
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Am+J+Transplant 2014 ; 14 (7): 1630-7 Nephropedia Template TP
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A Randomized, Prospective, Parallel Group Study of Laparoscopic vs Laparoendoscopic Single Site Donor Nephrectomy for Kidney Donation #MMPMID24934732Aull MJ; Afaneh C; Charlton M; Serur D; Douglas M; Christos PJ; Kapur S; Del Pizzo JJAm J Transplant 2014[Jul]; 14 (7): 1630-7 PMID24934732show ga
Few prospective, randomized studies have assessed benefits of laparoendoscopic single site donor nephrectomy (LESS-DN) over laparoscopic donor nephrectomy (LDN). Our center initiated such a trial in January 2011, following subjects randomized to LESS-DN vs. LDN from surgery through 5 years post-donation. Subjects complete recovery/satisfaction questionnaires at 2, 6, and 12 months post-donation; transplant recipient outcomes are also recorded. 100 subjects (49 LESS-DN, 51 LDN) underwent surgery; donor demographics were similar between groups, and included a predominance of female, living unrelated donors, mean age of 47 years who underwent left donor nephrectomy. Operative parameters (overall time, time to extraction, warm ischemia time, blood loss) were similar between groups. Conversion to hand-assist laparoscopy was required in 3 LESS-DN (6.1%) vs. 2 LDN (3.9%; P=0.67). Questionnaires revealed 97.2% of LESS-DN vs. 79.5% of LDN (P=0.03) were 100% recovered by two months after donation. No significant difference was seen in satisfaction scores between the groups. Recipient outcomes were similar between groups. Our randomized trial comparing LESS donor nephrectomy to LDN confirms that LESS-DN offers a safe alternative to conventional LDN in terms of intra- and post-operative complications. LDN and LESS-DN offer similar recovery and satisfaction after donation.�
  
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