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10.2215/CJN.06470614 http://scihub22266oqcxt.onion/10.2215/CJN.06470614 C4386251!4386251!25717073     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25717073.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Clin+J+Am+Soc+Nephrol 2015 ; 10 (4): 601-10 Nephropedia Template TP {{tp|p=25717073|t=2015. Estimating GFR in Adult Patients with Hematopoietic Cell Transplant: Comparison of Estimating Equations with an Iohexol Reference Standard |pdf=|usr=}}{{25717073}} gab.com Text Estimating GFR in Adult Patients with Hematopoietic Cell Transplant: Comparison of Estimating Equations with an Iohexol Reference Standard JO: Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25717073 #FOAvip Background and objectives: Formal evaluation of kidney function before and after hematopoietic cell transplant is important to determine conditioning regimens, type of transplant, and medication dosing. Serum creatinine and estimating equations may not accurately assess kidney function. Design, study, participants, & measurements: Existing estimating equations for GFR were compared with an iohexol measure of GFR in a prospective cohort study of 50 patients undergoing hematopoietic cell transplant and subsequent care at the Fred Hutchinson Cancer Research Institute from 2009 to 2013. Patients underwent iohexol GFR, serum creatinine, and cystatin C determination at baseline and day 100 posthematopoietic cell transplant. Iohexol GFR measurements were compared with the CKD Epidemiology Collaboration, Inker CKD Epidemiology Collaboration cystatin C with and without serum creatinine, Modification of Diet in Renal Disease, and Cockcroft?Gault estimating equations using Bland?Altman analysis and McNemar?s test. The iohexol measurements were also compared with blood samples collected simultaneously on filter paper. Results: Mean differences between iohexol GFR and eGFR on the basis of Bland?Altman analyses ranged from ?20.6 to +15.4 ml/min per 1.73 m2 at baseline and ?12.7 to +12.9 ml/min per 1.73 m2 at day 100. The CKD Epidemiology Collaboration and Modification of Diet in Renal Disease estimating equations classified 64% of patients with a GFR<90 at baseline compared with 38% by iohexol GFR (P=0.003 and P<0.01, respectively). No statistically significant differences were seen at day 100. The filter paper GFR had a mean difference of 0 at baseline and 5.9 at day 100. Additionally, 21%?37% and 57%?89% of eGFRs were within 10% and 30%, respectively, of the iohexol GFR at baseline, and 16%?34% and 72%?84% were within 10% and 30%, respectively, of the iohexol GFR at day 100; 98% of the filter paper estimates at baseline were within 30%, and 46% were within 10% of iohexol GFR. Conclusions: The estimating equations are neither accurate nor precise in the hematopoietic cell transplant population, and clinical decision may require measurement of GFR. Twit Text FOAVip Estimating GFR in Adult Patients with Hematopoietic Cell Transplant: Comparison of Estimating Equations with an Iohexol Reference Standard ????Clin J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=25717073 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25717073 #FOAvip English Wikipedia <ref>{{Cite pmid|25717073}}</ref> Estimating GFR in Adult Patients with Hematopoietic Cell Transplant: Comparison of Estimating Equations with an Iohexol Reference Standard #MMPMID25717073 Hingorani S; Pao E; Schoch G; Gooley T; Schwartz GJ Clin J Am Soc Nephrol 2015[Apr]; 10 (4): 601-10 PMID25717073show ga Background and objectives: Formal evaluation of kidney function before and after hematopoietic cell transplant is important to determine conditioning regimens, type of transplant, and medication dosing. Serum creatinine and estimating equations may not accurately assess kidney function. Design, study, participants, & measurements: Existing estimating equations for GFR were compared with an iohexol measure of GFR in a prospective cohort study of 50 patients undergoing hematopoietic cell transplant and subsequent care at the Fred Hutchinson Cancer Research Institute from 2009 to 2013. Patients underwent iohexol GFR, serum creatinine, and cystatin C determination at baseline and day 100 posthematopoietic cell transplant. Iohexol GFR measurements were compared with the CKD Epidemiology Collaboration, Inker CKD Epidemiology Collaboration cystatin C with and without serum creatinine, Modification of Diet in Renal Disease, and Cockcroft?Gault estimating equations using Bland?Altman analysis and McNemar?s test. The iohexol measurements were also compared with blood samples collected simultaneously on filter paper. Results: Mean differences between iohexol GFR and eGFR on the basis of Bland?Altman analyses ranged from ?20.6 to +15.4 ml/min per 1.73 m2 at baseline and ?12.7 to +12.9 ml/min per 1.73 m2 at day 100. The CKD Epidemiology Collaboration and Modification of Diet in Renal Disease estimating equations classified 64% of patients with a GFR<90 at baseline compared with 38% by iohexol GFR (P=0.003 and P<0.01, respectively). No statistically significant differences were seen at day 100. The filter paper GFR had a mean difference of 0 at baseline and 5.9 at day 100. Additionally, 21%?37% and 57%?89% of eGFRs were within 10% and 30%, respectively, of the iohexol GFR at baseline, and 16%?34% and 72%?84% were within 10% and 30%, respectively, of the iohexol GFR at day 100; 98% of the filter paper estimates at baseline were within 30%, and 46% were within 10% of iohexol GFR. Conclusions: The estimating equations are neither accurate nor precise in the hematopoietic cell transplant population, and clinical decision may require measurement of GFR. äEstimating GFR in Adult Patients with Hematopoietic Cell Transplant: C(epmc).pdf DeepDyve Pubget Overpricing