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10.1093/carcin/bgv017

http://scihub22266oqcxt.onion/10.1093/carcin/bgv017
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suck abstract from ncbi


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pmid25750173      Carcinogenesis 2015 ; 36 (4): 459-68
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  • Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial?mesenchymal transition #MMPMID25750173
  • Liu H; Ren G; Wang T; Chen Y; Gong C; Bai Y; Wang B; Qi H; Shen J; Zhu L; Qian C; Lai M; Shao J
  • Carcinogenesis 2015[Apr]; 36 (4): 459-68 PMID25750173show ga
  • This study describes a novel mechanism of the inflammatory cytokine IL-6 induced Fra-1 upregulation through activating STAT3 by phosphorylation and acetylation, and demonstrates that this signaling pathway plays a critical role in promoting epithelial?mesenchymal transition and aggressiveness of colorectal cancer.



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