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10.1074/jbc.M115.645903 http://scihub22266oqcxt.onion/10.1074/jbc.M115.645903 C4424331!4424331!25802332     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=25802332&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25802332.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Biol+Chem 2015 ; 290 (19): 11918-34 Nephropedia Template TP {{tp|p=25802332|t=2015. Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-? Signaling in the Retinal Pigment Epithelium* |pdf=|usr=}}{{25802332}} gab.com Text Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)- Signaling in the Retinal Pigment Epithelium* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25802332 #FOAvip Background: Human age-related macular degeneration (AMD) retinas exhibit iron overload and localized C3 accumulation in the retinal pigment epithelium (RPE).Results: Iron induces C3 expression via ERK1/2, SMAD3, and CCAAT/enhancer-binding protein-? (C/EBP-?) in a non-canonical TGF-? signaling pathway.Conclusion: An iron-mediated pathway leads to complement dysregulation, an etiologic feature of AMD.Significance: Regulating iron-induced C3 expression suggests a novel therapeutic approach for AMD. Twit Text FOAVip Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)- Signaling in the Retinal Pigment Epithelium* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=25802332 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25802332 #FOAvip English Wikipedia <ref>{{Cite pmid|25802332}}</ref> Iron-induced Local Complement Component 3 (C3) Up-regulation via Non-canonical Transforming Growth Factor (TGF)-? Signaling in the Retinal Pigment Epithelium* #MMPMID25802332 Li Y; Song D; Song Y; Zhao L; Wolkow N; Tobias JW; Song W; Dunaief JL J Biol Chem 2015[May]; 290 (19): 11918-34 PMID25802332show ga Background: Human age-related macular degeneration (AMD) retinas exhibit iron overload and localized C3 accumulation in the retinal pigment epithelium (RPE).Results: Iron induces C3 expression via ERK1/2, SMAD3, and CCAAT/enhancer-binding protein-? (C/EBP-?) in a non-canonical TGF-? signaling pathway.Conclusion: An iron-mediated pathway leads to complement dysregulation, an etiologic feature of AMD.Significance: Regulating iron-induced C3 expression suggests a novel therapeutic approach for AMD. äIron-induced Local Complement Component 3 (C3) Up-regulation via Non-c(epmc).pdf DeepDyve Pubget Overpricing