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10.1074/jbc.M114.623421

http://scihub22266oqcxt.onion/10.1074/jbc.M114.623421
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C4432301!4432301!25839231
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suck abstract from ncbi


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pmid25839231      J+Biol+Chem 2015 ; 290 (20): 12858-67
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  • Thrombospondin-1 (TSP1)-producing B Cells Restore Antigen (Ag)-specific Immune Tolerance in an Allergic Environment* #MMPMID25839231
  • Yang G; Geng XR; Liu ZQ; Liu JQ; Liu XY; Xu LZ; Zhang HP; Sun YX; Liu ZG; Yang PC
  • J Biol Chem 2015[May]; 290 (20): 12858-67 PMID25839231show ga
  • Background: The generation of tolerogenic dendritic cells (TolDCs) in an allergic environment is refractory.Results: Administration of IL-13 antagonists increases TolDCs in an allergic environment.Conclusion: Blocking IL-13 in an allergic environment facilitates the generation of TolDCs.Significance: Using IL-13 antagonists has the potential to enhance the therapeutic effect of the allergic diseases.
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