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10.1016/j.tibs.2014.09.003 http://scihub22266oqcxt.onion/10.1016/j.tibs.2014.09.003 C4435807!4435807!25440716     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25440716.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Trends+Biochem+Sci 2014 ; 39 (11): 556-69 Nephropedia Template TP {{tp|p=25440716|t=2014. Ultrasensitivity Part II: Multisite phosphorylation, stoichiometric inhibitors, and positive feedback |pdf=|usr=}}{{25440716}} gab.com Text Ultrasensitivity Part II: Multisite phosphorylation, stoichiometric inhibitors, and positive feedback JO: Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25440716 #FOAvip In this series of reviews we are examining ultrasensitive responses, the switch-like input-output relationships that contribute to signal processing in a wide variety of signaling contexts. In the first part of this series we examined one mechanism for generating ultrasensitivity, zero-order ultrasensitivity, where the saturation of two converting enzymes allows the output to switch from low to high over a tight range of input levels. In this second installment, we focus on three conceptually distinct mechanisms for ultrasensitivity: multisite phosphorylation, stoichiometric inhibitors, and positive feedback. We also examine several related mechanisms and concepts, including cooperativity, reciprocal regulation, coherent feedforward regulation, and substrate competition, and provide several examples of signaling processes where these mechanisms are known or are suspected to be applicable. Twit Text FOAVip Ultrasensitivity Part II: Multisite phosphorylation, stoichiometric inhibitors, and positive feedback ????Trends Biochem Sci http://www.kidney.de/pget.php?&tw=1&pmid=25440716 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25440716 #FOAvip English Wikipedia <ref>{{Cite pmid|25440716}}</ref> Ultrasensitivity Part II: Multisite phosphorylation, stoichiometric inhibitors, and positive feedback #MMPMID25440716 Ferrell JE; Ha SH Trends Biochem Sci 2014[Nov]; 39 (11): 556-69 PMID25440716show ga In this series of reviews we are examining ultrasensitive responses, the switch-like input-output relationships that contribute to signal processing in a wide variety of signaling contexts. In the first part of this series we examined one mechanism for generating ultrasensitivity, zero-order ultrasensitivity, where the saturation of two converting enzymes allows the output to switch from low to high over a tight range of input levels. In this second installment, we focus on three conceptually distinct mechanisms for ultrasensitivity: multisite phosphorylation, stoichiometric inhibitors, and positive feedback. We also examine several related mechanisms and concepts, including cooperativity, reciprocal regulation, coherent feedforward regulation, and substrate competition, and provide several examples of signaling processes where these mechanisms are known or are suspected to be applicable. äUltrasensitivity Part II: Multisite phosphorylation, stoichiometric in(epmc).pdf DeepDyve Pubget Overpricing