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Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor #MMPMID25814526
Xiang Y; Cheng J; Wang D; Hu X; Xie Y; Stitham J; Atteya G; Du J; Tang WH; Lee SH; Leslie K; Spollett G; Liu Z; Herzog E; Herzog RI; Lu J; Martin KA; Hwa J
Blood 2015[May]; 125 (22): 3377-87 PMID25814526show ga
miR-24 tightly regulates VWF expression, maturation, and secretion.Hyperglycemia regulates VWF through aldose reductase, ROS, and c-Myc.