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10.1016/j.gdata.2014.11.002 http://scihub22266oqcxt.onion/10.1016/j.gdata.2014.11.002 C4535743!4535743!26484144     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26484144.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genom+Data 2015 ; 3 (ä): 28-32 Nephropedia Template TP {{tp|p=26484144|t=2015. The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation |pdf=|usr=}}{{26484144}} gab.com Text The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation JO: Genom Data http://www.kidney.de/pget.php?&tw=1&pmid=26484144 #FOAvip The protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) induces transition of the epithelial MCF-7 cell line to a mesenchymal phenotype. A subset of the resulting mesenchymal cells has surface markers characteristics of a cancer stem cell (CSC) population. We profiled the transcriptome changes associated with the epithelial to mesenchymal transition and those that occurred in the CSC subset. Using a siRNA knockdown strategy, we examined the extent to which these changes were dependent on the PKC family member, PKC-?. The importance of the cytoplasmic signaling role of this kinase is well established and in this study, we have shown by PKC-? ChIP-sequencing analysis that this kinase has a dual role with the ability to also associate with chromatin on a subset of PKC-? dependent genes. In the associated manuscript (Zafar et al., 2014 [5]) we presented evidence for the first time showing that this nuclear role of PKC-? is also important for gene induction and mesenchymal/CSC phenotype. Here we describe the analysis associated with the transcriptome and ChIP-seq data presented in Zafar et al. (2014) [5] and uploaded to NCBI Gene Expression Omnibus (GSE53335). Twit Text FOAVip The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation ????Genom Data http://www.kidney.de/pget.php?&tw=1&pmid=26484144 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26484144 #FOAvip English Wikipedia <ref>{{Cite pmid|26484144}}</ref> The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation #MMPMID26484144 Zafar A; Hardy K; Wu F; Li J; Rao S Genom Data 2015[Mar]; 3 (ä): 28-32 PMID26484144show ga The protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) induces transition of the epithelial MCF-7 cell line to a mesenchymal phenotype. A subset of the resulting mesenchymal cells has surface markers characteristics of a cancer stem cell (CSC) population. We profiled the transcriptome changes associated with the epithelial to mesenchymal transition and those that occurred in the CSC subset. Using a siRNA knockdown strategy, we examined the extent to which these changes were dependent on the PKC family member, PKC-?. The importance of the cytoplasmic signaling role of this kinase is well established and in this study, we have shown by PKC-? ChIP-sequencing analysis that this kinase has a dual role with the ability to also associate with chromatin on a subset of PKC-? dependent genes. In the associated manuscript (Zafar et al., 2014 [5]) we presented evidence for the first time showing that this nuclear role of PKC-? is also important for gene induction and mesenchymal/CSC phenotype. Here we describe the analysis associated with the transcriptome and ChIP-seq data presented in Zafar et al. (2014) [5] and uploaded to NCBI Gene Expression Omnibus (GSE53335). äThe role of protein kinase-C theta in control of epithelial to mesench(epmc).pdf DeepDyve Pubget Overpricing