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10.1101/gad.269068.115

http://scihub22266oqcxt.onion/10.1101/gad.269068.115
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C4573856!4573856!26294658
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suck abstract from ncbi


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pmid26294658      Genes+Dev 2015 ; 29 (17): 1835-49
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  • Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation #MMPMID26294658
  • Peter D; Weber R; Köne C; Chung MY; Ebertsch L; Truffault V; Weichenrieder O; Igreja C; Izaurralde E
  • Genes Dev 2015[Sep]; 29 (17): 1835-49 PMID26294658show ga
  • Peter et al. present the crystal structures of the eIF4E-binding regions of the Drosophila melanogaster (Dm) and Caenorhabditis elegans (Ce) Mxt proteins in complex with eIF4E in the cap-bound and cap-free states. The structures reveal unexpected diversity in the binding modes of 4E-BPs, resulting in eIF4E complexes that display differential sensitivity to 4E-BP regulation.
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