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10.1155/2015/485839 http://scihub22266oqcxt.onion/10.1155/2015/485839 C4620414!4620414!26543646     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26543646&cmd=llinks): Failed to open stream: HTTP request failed! 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The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease |pdf=|usr=}}{{26543646}} gab.com Text The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease JO: Int J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=26543646 #FOAvip Current data suggests that statins might have beneficial effects on renal outcomes. Beneficial effects of statin treatment on renal progression in advanced chronic kidney disease (CKD) are obviously controversial. In a retrospective, controlled study, the authors have evaluated the effects of 53-week treatment with simvastatin, versus no treatment on proteinuria and renal function among 51 patients with CKD stages III-IV. By the end of the 53-week treatment, urine protein excretion decreased from 0.96 (IQR 0.54, 2.9) to 0.48 (IQR 0.18, 0.79)?g/g creatinine (P < 0.001) in patients treated with simvastatin in addition to ACEI and ARBs, while no change was observed among the untreated patients. Moreover, a significantly greater decrease in urine protein excretion was observed in the simvastatin group as compared with the untreated group. The mean changes of serum creatinine and eGFR did not significantly differ in both groups. A significantly greater decrease in total cholesterol and LDL-cholesterol was found in the simvastatin group than in the untreated group. In summary, apart from lipid lowering among CKD patients, ingesting simvastatin was associated with a decrease in proteinuria. These statin effects may become important for supportive therapy in renal damage in the future. Twit Text FOAVip The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease ????Int J Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=26543646 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26543646 #FOAvip English Wikipedia <ref>{{Cite pmid|26543646}}</ref> The Effects of Simvastatin on Proteinuria and Renal Function in Patients with Chronic Kidney Disease #MMPMID26543646 Satirapoj B; Promrattanakun A; Supasyndh O; Choovichian P Int J Nephrol 2015[]; 2015 (�): � PMID26543646show ga Current data suggests that statins might have beneficial effects on renal outcomes. Beneficial effects of statin treatment on renal progression in advanced chronic kidney disease (CKD) are obviously controversial. In a retrospective, controlled study, the authors have evaluated the effects of 53-week treatment with simvastatin, versus no treatment on proteinuria and renal function among 51 patients with CKD stages III-IV. By the end of the 53-week treatment, urine protein excretion decreased from 0.96 (IQR 0.54, 2.9) to 0.48 (IQR 0.18, 0.79)?g/g creatinine (P < 0.001) in patients treated with simvastatin in addition to ACEI and ARBs, while no change was observed among the untreated patients. Moreover, a significantly greater decrease in urine protein excretion was observed in the simvastatin group as compared with the untreated group. The mean changes of serum creatinine and eGFR did not significantly differ in both groups. A significantly greater decrease in total cholesterol and LDL-cholesterol was found in the simvastatin group than in the untreated group. In summary, apart from lipid lowering among CKD patients, ingesting simvastatin was associated with a decrease in proteinuria. These statin effects may become important for supportive therapy in renal damage in the future. �The Effects of Simvastatin on Proteinuria and Renal Function in Patien(epmc).pdf DeepDyve Pubget Overpricing