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10.1186/s13046-015-0245-3 http://scihub22266oqcxt.onion/10.1186/s13046-015-0245-3 C4625617!4625617!26514226     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26514226.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Exp+Clin+Cancer+Res 2015 ; 34 (ä): ä Nephropedia Template TP {{tp|p=26514226|t=2015. HOXD9 promotes epithelial?mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma |pdf=|usr=}}{{26514226}} gab.com Text HOXD9 promotes epithelial mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma JO: J Exp Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=26514226 #FOAvip Hepatocellular carcinoma (HCC) is a common malignant tumor that severely threatens human health. The poor prognosis of HCC is mainly attributed to intrahepatic and extrahepatic metastases. HOXD9 proteins belong to a superfamily that regulates the development and control of many cellular processes, including proliferation, apoptosis, cell shape, and cell migration. HOXD9 can also function as an oncogene in several cancer cells. However, its biological function in human HCC requires further investigation. In this study, HOXD9 exhibited high expression in invasive HCC cells. HOXD9 overexpression can significantly enhance HCC cell migration, invasion, and metastasis, whereas silencing HOXD9 inhibits these processes. HOXD9 also promotes the epithelial?mesenchymal transition (EMT) of HCC cells. Microarray analysis suggests that ZEB1 can function as a downstream factor of HOXD9. HOXD9 can interact with the promoter region of ZEB1 and promotes ZEB1 expression. ZEB1 knockdown inhibits HOXD9-induced migration and invasion, as well as EMT in HCC cells. This study helps elucidates the oncogenic functions of HOXD9 in HCC.Electronic supplementary material: The online version of this article (doi:10.1186/s13046-015-0245-3) contains supplementary material, which is available to authorized users. Twit Text FOAVip HOXD9 promotes epithelial mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma ????J Exp Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=26514226 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26514226 #FOAvip English Wikipedia <ref>{{Cite pmid|26514226}}</ref> HOXD9 promotes epithelial?mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma #MMPMID26514226 Lv X; Li L; Lv L; Qu X; Jin S; Li K; Deng X; Cheng L; He H; Dong L J Exp Clin Cancer Res 2015[]; 34 (ä): ä PMID26514226show ga Hepatocellular carcinoma (HCC) is a common malignant tumor that severely threatens human health. The poor prognosis of HCC is mainly attributed to intrahepatic and extrahepatic metastases. HOXD9 proteins belong to a superfamily that regulates the development and control of many cellular processes, including proliferation, apoptosis, cell shape, and cell migration. HOXD9 can also function as an oncogene in several cancer cells. However, its biological function in human HCC requires further investigation. In this study, HOXD9 exhibited high expression in invasive HCC cells. HOXD9 overexpression can significantly enhance HCC cell migration, invasion, and metastasis, whereas silencing HOXD9 inhibits these processes. HOXD9 also promotes the epithelial?mesenchymal transition (EMT) of HCC cells. Microarray analysis suggests that ZEB1 can function as a downstream factor of HOXD9. HOXD9 can interact with the promoter region of ZEB1 and promotes ZEB1 expression. ZEB1 knockdown inhibits HOXD9-induced migration and invasion, as well as EMT in HCC cells. This study helps elucidates the oncogenic functions of HOXD9 in HCC.Electronic supplementary material: The online version of this article (doi:10.1186/s13046-015-0245-3) contains supplementary material, which is available to authorized users. äHOXD9 promotes epithelial?mesenchymal transition and cancer metastasis(epmc).pdf DeepDyve Pubget Overpricing