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10.1186/s40348-015-0024-4 http://scihub22266oqcxt.onion/10.1186/s40348-015-0024-4 C4666883!4666883!26626346     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26626346.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Cell+Pediatr 2015 ; 2 (ä): ä Nephropedia Template TP {{tp|p=26626346|t=2015. GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn?s disease |pdf=|usr=}}{{26626346}} gab.com Text GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn s disease JO: Mol Cell Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=26626346 #FOAvip Background: Intestinal monocytes/macrophages sustain the intestinal immune homeostasis and might be an attractive therapeutic target for the management of inflammatory bowel disease (IBD). Granulocyte macrophage colony-stimulating factor (GM-CSF) exerts beneficial effects on intestinal inflammation and promotes signal transducer and activator of transcription 3 (STAT3)-mediated expansion of myeloid-derived suppressor cells (MDSCs). However, the full action mechanism of GM-CSF, and especially whether monocytes mediate its therapeutic effects in vivo, had not been previously elucidated. Conclusions: This review article summarizes recent developments in the immunology of mucosal diseases and describes new aspects of the role of myeloid regulatory cells in IBD and the function of GM-CSF in maintaining the intestinal immune homeostasis in Crohn?s disease (CD). This review article highlights the exploration of stimulating in addition to suppressive therapies for patients with IBD and underpins that myeloid regulatory cells might become a promising novel cell-based therapeutic option. Twit Text FOAVip GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn s disease ????Mol Cell Pediatr http://www.kidney.de/pget.php?&tw=1&pmid=26626346 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26626346 #FOAvip English Wikipedia <ref>{{Cite pmid|26626346}}</ref> GM-CSF and the role of myeloid regulatory cells in the pathogenesis and treatment of Crohn?s disease #MMPMID26626346 Däbritz J Mol Cell Pediatr 2015[Dec]; 2 (ä): ä PMID26626346show ga Background: Intestinal monocytes/macrophages sustain the intestinal immune homeostasis and might be an attractive therapeutic target for the management of inflammatory bowel disease (IBD). Granulocyte macrophage colony-stimulating factor (GM-CSF) exerts beneficial effects on intestinal inflammation and promotes signal transducer and activator of transcription 3 (STAT3)-mediated expansion of myeloid-derived suppressor cells (MDSCs). However, the full action mechanism of GM-CSF, and especially whether monocytes mediate its therapeutic effects in vivo, had not been previously elucidated. Conclusions: This review article summarizes recent developments in the immunology of mucosal diseases and describes new aspects of the role of myeloid regulatory cells in IBD and the function of GM-CSF in maintaining the intestinal immune homeostasis in Crohn?s disease (CD). This review article highlights the exploration of stimulating in addition to suppressive therapies for patients with IBD and underpins that myeloid regulatory cells might become a promising novel cell-based therapeutic option. äGM-CSF and the role of myeloid regulatory cells in the pathogenesis an(epmc).pdf DeepDyve Pubget Overpricing