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10.1073/pnas.1525697113 http://scihub22266oqcxt.onion/10.1073/pnas.1525697113 C4776485!4776485!26858439     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26858439.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (8): 2223-8 Nephropedia Template TP {{tp|p=26858439|t=2016. Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors |pdf=|usr=}}{{26858439}} gab.com Text Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26858439 #FOAvip A recent paradigm shift has established ?tumor cell seeding? as an intriguing biological phenomenon in cancer biology. However, the clinical implications of a bidirectional flow of cancer cells remains largely unexplored. We show that systemic administration of TNF-expressing cancer cells reduces growth of both primary tumors and metastatic colonies defined here as ?tumor self-targeting.? Our findings support a provocative concept in which circulating tumor cells genetically manipulated ex vivo and readministered into the circulating bloodstream may indeed serve as tumor-targeted cellular vectors in preclinical settings and could potentially open a field of translational investigation. Twit Text FOAVip Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=26858439 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26858439 #FOAvip English Wikipedia <ref>{{Cite pmid|26858439}}</ref> Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors #MMPMID26858439 Dondossola E; Dobroff AS; Marchiò S; Cardó-Vila M; Hosoya H; Libutti SK; Corti A; Sidman RL; Arap W; Pasqualini R Proc Natl Acad Sci U S A 2016[Feb]; 113 (8): 2223-8 PMID26858439show ga A recent paradigm shift has established ?tumor cell seeding? as an intriguing biological phenomenon in cancer biology. However, the clinical implications of a bidirectional flow of cancer cells remains largely unexplored. We show that systemic administration of TNF-expressing cancer cells reduces growth of both primary tumors and metastatic colonies defined here as ?tumor self-targeting.? Our findings support a provocative concept in which circulating tumor cells genetically manipulated ex vivo and readministered into the circulating bloodstream may indeed serve as tumor-targeted cellular vectors in preclinical settings and could potentially open a field of translational investigation. äSelf-targeting of TNF-releasing cancer cells in preclinical models of (epmc).pdf DeepDyve Pubget Overpricing