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10.3238/arztebl.2016.0129 http://scihub22266oqcxt.onion/10.3238/arztebl.2016.0129 C4800158!4800158!26976713     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26976713&cmd=llinks): Failed to open stream: HTTP request failed! 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The Periprocedural Management of Anticoagulation and Platelet Aggregation Inhibitors in Endoscopic Interventions |pdf=|usr=}}{{26976713}} gab.com Text The Periprocedural Management of Anticoagulation and Platelet Aggregation Inhibitors in Endoscopic Interventions JO: Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=26976713 #FOAvip Background: In Germany, more than half a million persons, most of them elderly, are under long-term treatment with anticoagulants. The approval of new oral anticoagulants and platelet aggregation inhibitors, as well as new data on periprocedural bridging with heparins, have introduced marked complexity to the management of treatment with anticoagulants and platelet aggregation inhibitors for endoscopic interventions in visceral surgery. Method: This review is based on pertinent publications retrieved by a selective literature search in PubMed, as well as on the relevant guidelines. Results: Robust data are available on the management of vitamin K antagonists (VKA) and platelet aggregation inhibitors for endoscopic procedures; on the other hand, the data on the periprocedural management of non-VKA oral anticoagulants (NOAC) are still inadequate. Endoscopic procedures that carry a low risk of bleeding can be performed under treatment with anticoagulants or platelet aggregation inhibitors. Before any procedure with a high risk of bleeding (? 1.5%) oral anticoagulants of any type and P2Y12 inhibitors should generally be discontinued. Patients in whom VKA are temporarily discontinued for this reason need bridging treatment with heparin only if they are at high risk of thromboembolic events (?10% per year). For patients who are anticoagulated with NOAC, timely discontinuation of the drug depending on renal function is of key importance, and bridging is usually unnecessary. Conclusion: Adequate scientific evidence supports the current recommendations and treatment algorithms for the periprocedural management of oral anticoagulants and platelet aggregation inhibitors in endoscopic procedures. Larger-scale studies are still needed to provide a sound basis for the corresponding recommendations about NOAC. Twit Text FOAVip The Periprocedural Management of Anticoagulation and Platelet Aggregation Inhibitors in Endoscopic Interventions ????Dtsch Arztebl Int http://www.kidney.de/pget.php?&tw=1&pmid=26976713 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26976713 #FOAvip English Wikipedia <ref>{{Cite pmid|26976713}}</ref> The Periprocedural Management of Anticoagulation and Platelet Aggregation Inhibitors in Endoscopic Interventions #MMPMID26976713 Lange CM; Fichtlscherer S; Miesbach W; Zeuzem S; Albert J Dtsch Arztebl Int 2016[Feb]; 113 (8): 129-35 PMID26976713show ga Background: In Germany, more than half a million persons, most of them elderly, are under long-term treatment with anticoagulants. The approval of new oral anticoagulants and platelet aggregation inhibitors, as well as new data on periprocedural bridging with heparins, have introduced marked complexity to the management of treatment with anticoagulants and platelet aggregation inhibitors for endoscopic interventions in visceral surgery. Method: This review is based on pertinent publications retrieved by a selective literature search in PubMed, as well as on the relevant guidelines. Results: Robust data are available on the management of vitamin K antagonists (VKA) and platelet aggregation inhibitors for endoscopic procedures; on the other hand, the data on the periprocedural management of non-VKA oral anticoagulants (NOAC) are still inadequate. Endoscopic procedures that carry a low risk of bleeding can be performed under treatment with anticoagulants or platelet aggregation inhibitors. Before any procedure with a high risk of bleeding (? 1.5%) oral anticoagulants of any type and P2Y12 inhibitors should generally be discontinued. Patients in whom VKA are temporarily discontinued for this reason need bridging treatment with heparin only if they are at high risk of thromboembolic events (?10% per year). For patients who are anticoagulated with NOAC, timely discontinuation of the drug depending on renal function is of key importance, and bridging is usually unnecessary. Conclusion: Adequate scientific evidence supports the current recommendations and treatment algorithms for the periprocedural management of oral anticoagulants and platelet aggregation inhibitors in endoscopic procedures. Larger-scale studies are still needed to provide a sound basis for the corresponding recommendations about NOAC. äThe Periprocedural Management of Anticoagulation and Platelet Aggregat(epmc).pdf DeepDyve Pubget Overpricing